Cortical-subcortical interactions in goal-directed behavior
Flexibly selecting appropriate actions in response to complex, ever-changing environments
requires both cortical and subcortical regions, which are typically described as participating …
requires both cortical and subcortical regions, which are typically described as participating …
The superior colliculus: cell types, connectivity, and behavior
The superior colliculus (SC), one of the most well-characterized midbrain sensorimotor
structures where visual, auditory, and somatosensory information are integrated to initiate …
structures where visual, auditory, and somatosensory information are integrated to initiate …
Striatal indirect pathway mediates exploration via collicular competition
J Lee, BL Sabatini - Nature, 2021 - nature.com
The ability to suppress actions that lead to a negative outcome and explore alternative
actions is necessary for optimal decision making. Although the basal ganglia have been …
actions is necessary for optimal decision making. Although the basal ganglia have been …
Diverse inhibitory projections from the cerebellar interposed nucleus
EN Judd, SM Lewis, AL Person - Elife, 2021 - elifesciences.org
The cerebellum consists of parallel circuit modules that contribute to diverse behaviors,
spanning motor to cognitive. Recent work employing cell-type-specific tracing has identified …
spanning motor to cognitive. Recent work employing cell-type-specific tracing has identified …
Superior colliculus bidirectionally modulates choice activity in frontal cortex
Action selection occurs through competition between potential choice options. Neural
correlates of choice competition are observed across frontal cortex and downstream …
correlates of choice competition are observed across frontal cortex and downstream …
Pathway-specific inputs to the superior colliculus support flexible responses to visual threat
Behavioral flexibility requires directing feedforward sensory information to appropriate
targets. In the superior colliculus, divergent outputs orchestrate different responses to visual …
targets. In the superior colliculus, divergent outputs orchestrate different responses to visual …
Approaches to understanding multisensory dysfunction in autism spectrum disorder
JK Siemann, J Veenstra‐VanderWeele… - Autism …, 2020 - Wiley Online Library
Abnormal sensory responses are a DSM‐5 symptom of autism spectrum disorder (ASD),
and research findings demonstrate altered sensory processing in ASD. Beyond difficulties …
and research findings demonstrate altered sensory processing in ASD. Beyond difficulties …
The tectonigral pathway regulates appetitive locomotion in predatory hunting in mice
Appetitive locomotion is essential for animals to approach rewards, such as food and prey.
The neuronal circuitry controlling appetitive locomotion is unclear. In a goal-directed …
The neuronal circuitry controlling appetitive locomotion is unclear. In a goal-directed …
[HTML][HTML] The caudal prethalamus: Inhibitory switchboard for behavioral control?
Prethalamic nuclei in the mammalian brain include the zona incerta, the ventral lateral
geniculate nucleus, and the intergeniculate leaflet, which provide long-range inhibition to …
geniculate nucleus, and the intergeniculate leaflet, which provide long-range inhibition to …
Recent advances in the understanding of specific efferent pathways emerging from the cerebellum
S Kang, S Jun, SJ Baek, H Park, Y Yamamoto… - Frontiers in …, 2021 - frontiersin.org
The cerebellum has a long history in terms of research on its network structures and motor
functions, yet our understanding of them has further advanced in recent years owing to …
functions, yet our understanding of them has further advanced in recent years owing to …