The Fetal Alcohol Spectrum Disorders—An Overview of Experimental Models, Therapeutic Strategies, and Future Research Directions

M Król, P Skowron, K Skowron, K Gil - Children, 2024 - mdpi.com
Since the establishment of a clear link between maternal alcohol consumption during
pregnancy and certain birth defects, the research into the treatment of FASD has become …

Developmental alcohol exposure in Drosophila: effects on adult phenotypes and gene expression in the brain

SS Mokashi, V Shankar, RA MacPherson… - Frontiers in …, 2021 - frontiersin.org
Fetal alcohol exposure can lead to developmental abnormalities, intellectual disability, and
behavioral changes, collectively termed fetal alcohol spectrum disorder (FASD). In 2015, the …

Looking at Developmental Neurotoxicity Testing from the Perspective of an Invertebrate Embryo

G Bicker - International journal of molecular sciences, 2022 - mdpi.com
Developmental neurotoxicity (DNT) of chemical compounds disrupts the formation of a
normal brain. There is impressive progress in the development of alternative testing …

Modulation of the Drosophila transcriptome by developmental exposure to alcohol

TV Morozova, V Shankar, RA MacPherson… - BMC genomics, 2022 - Springer
Background Prenatal exposure to ethanol can cause fetal alcohol spectrum disorder
(FASD), a prevalent, preventable pediatric disorder. Identifying genetic risk alleles for FASD …

Perspectives for advancing neurotoxicity studies with Drosophila

CR Beamish, A Dey, S Sarkar, MD Rand - Advances in Neurotoxicology, 2023 - Elsevier
Drosophila melanogaster, commonly known as the fruit fly, has been used as a model
system to answer fundamental biological questions for more than a century. Several …

From Natural Behavior to Drug Screening: Invertebrates as Models to Study Mechanisms Associated with Alcohol Use Disorders

H Scholz - 2023 - Springer
Humans consume ethanol-containing beverages, which may cause an uncontrollable or
difficult-to-control intake of ethanol-containing liquids and may result in alcohol use …

Modulation of the Drosophila Transcriptome by Developmental Exposure to Alcohol

R ANHOLT, TV Morozova, V Shankar, RA MacPherson… - 2022 - researchsquare.com
Background: Prenatal exposure to ethanol can cause fetal alcohol spectrum disorder
(FASD), a prevalent, preventable pediatric disorder. Identifying genetic risk alleles for FASD …

The Effects of Alcohol on the Developing Drosophila Nervous System

EE Hassoun - The Cardinal Edge, 2021 - ir.library.louisville.edu
Ethanol is the most common human teratogen, contributing to fetal alcohol syndrome (FAS)
when effects are the most severe. Key effects of fetal alcohol syndrome are observed in the …

[PDF][PDF] The Cardinal Edg e

EE Hassoun - ciazabezalkoholu.pl
Ethanol is the most common human teratogen, contributing to fetal alcohol syndrome (FAS)
when effects are the most severe. Key effects of fetal alcohol syndrome are observed in the …

Of Single Nucleotides and Single Cells: Charting the Genotype-Phenotype Map at High Resolution Using Drosophila Melanogaster

SS Mokashi - 2021 - search.proquest.com
Understanding the mechanisms by which genetic variation brings about phenotypic
variation is essential for understanding variation in complex traits.< i> Drosophila …