Regeneration is the process by which organisms replace lost or damaged tissue, and
regenerative capacity can vary greatly among species, tissues and life stages. Tissue …

Tuft cells—rare solitary chemosensory cells in mucosal epithelia—are undergoing intense
scientific scrutiny fueled by recent discovery of unsuspected connections to type 2 immunity …

Altered olfactory function is a common symptom of COVID-19, but its etiology is unknown. A
key question is whether SARS-CoV-2 (CoV-2)–the causal agent in COVID-19–affects …

Recent reports suggest an association between COVID-19 and altered olfactory function.
Here we analyze bulk and single cell RNA-Seq datasets to identify cell types in the olfactory …

The genome is partitioned into topologically associated domains and genomic
compartments with shared chromatin valence. This architecture is constrained by the DNA …

Epithelial surfaces form critical barriers to the outside world and are continuously renewed
by adult stem cells. Whereas dynamics of epithelial stem cells during homeostasis are …

SARS-CoV-2 infects less than 1% of cells in the human body, yet it can cause severe
damage in a variety of organs. Thus, deciphering the non-cell-autonomous effects of SARS …

The accessibility and transparency of the cornea permit robust stem cell labeling and in vivo
cell fate mapping. Limbal epithelial stem cells (LSCs) that renew the cornea are traditionally …

Although olfactory mucosa possesses long-lived horizontal basal stem cells (HBCs) and
remarkable regenerative capacity, the function of human olfactory neuroepithelium is …

SARS-CoV-2 infection causes a wide spectrum of clinical manifestations in humans, and
olfactory dysfunction is one of the most predictive and common symptoms in COVID-19 …