Insulin resistance is a major underlying mechanism for the “metabolic syndrome”, which is
also known as insulin resistance syndrome. Metabolic syndrome is increasing at an …

For many years, transcription factor Sp1 was viewed as a basal transcription factor and
relegated to a role in the regulation of so‐called housekeeping genes. Identification of Sp1's …

Acute myeloid leukemia (AML) is a malignant tumor of the immature myeloid hematopoietic
cells in the bone marrow (BM). It is a highly heterogeneous disease, with rising morbidity …

Nanoparticle-based drug delivery (NDD) has emerged as a promising approach to
improving upon the efficacy of existing drugs and enabling the development of new …

Aberrant DNA hypermethylation contributes to myeloid leukemogenesis by silencing
structurally normal genes involved in hematopoiesis. MicroRNAs (miRNAs) are noncoding …

Purpose: The purpose of this study was to investigate the clinicopathologic significance and
potential role of miR-200b and miR-200c in the development and progression of gastric …

The biologic and clinical significance of KIT overexpression that associates with KIT gain-of-
function mutations occurring in subsets of acute myeloid leukemia (AML)(ie, core binding …

Purpose: miR-29b directly or indirectly targets genes involved in acute myeloid leukemia
(AML), namely, DNMT s, CDK6, SP1, KIT, and FLT3. Higher miR-29b pretreatment …

Periodontitis is a chronic infectious disease driven by dysbiosis, an imbalance between
commensal bacteria and the host organism. Periodontitis is a leading cause of tooth loss in …

Abstract Treatment options for older patients with acute myeloid leukemia (AML) and for
patients with relapsed/refractory AML are limited, and outcomes are poor. Decitabine, a …