The use of vancomycin powder in modern spine surgery: systematic review and meta-analysis of the clinical evidence

J Bakhsheshian, NS Dahdaleh, SK Lam, JW Savage… - World neurosurgery, 2015 - Elsevier
Background Surgical-site infections (SSIs) can lead to greater postoperative morbidity,
mortality, and health care costs. Despite current prophylactic measures, rates of SSIs have …

Intrasite vancomycin powder for the prevention of surgical site infection in spine surgery: a systematic literature review

DG Kang, TF Holekamp, SC Wagner, RA Lehman Jr - The Spine Journal, 2015 - Elsevier
Background context Deep surgical site infections (SSIs) following spinal surgery are a
significant burden to the patient, patient's family, and the health-care system. Because of …

Effect of intrawound vancomycin powder in operatively treated high-risk tibia fractures: a randomized clinical trial

RV O'Toole, M Joshi, AR Carlini, CK Murray… - JAMA …, 2021 - jamanetwork.com
Importance Despite the widespread use of systemic antibiotics to prevent infections in
surgically treated patients with fracture, high rates of surgical site infection persist. Objective …

A meta-analysis of spinal surgical site infection and vancomycin powder: a review

NR Khan, CJ Thompson, M DeCuypere… - … of Neurosurgery: Spine, 2014 - thejns.org
Object Surgical site infection (SSI) is a serious and costly complication of spinal surgery.
There have been several conflicting reports on the use of intrawound vancomycin powder in …

Complications from the use of intrawound vancomycin in lumbar spinal surgery: a systematic review

GM Ghobrial, DW Cadotte, K Williams, MG Fehlings… - Neurosurgical …, 2015 - thejns.org
OBJECT The use of intrawound vancomycin is rapidly being adopted for the prevention of
surgical site infection (SSI) in spinal surgery. At operative closure, the placement of …

Burden of Surgical Site Infections Associated with Select Spine Operations and Involvement of Staphylococcus aureus

H Patel, H Khoury, D Girgenti, S Welner, H Yu - Surgical infections, 2017 - liebertpub.com
Background: Spine operations may be indicated for treatment of diseases including
vertebral injuries, degenerative spinal conditions, disk disease, spinal misalignments, or …

Safety of topical vancomycin for pediatric spinal deformity: nontoxic serum levels with supratherapeutic drain levels

SJ Armaghani, TJ Menge, SA Lovejoy, GA Mencio… - Spine, 2014 - journals.lww.com
Study Design. Retrospective cohort analysis. Objective. To establish if drain levels exceed
the minimum inhibitory concentrations for common pathogens (methicillin-resistant …

Does intrawound application of vancomycin influence bone healing in spinal surgery?

C Eder, S Schenk, J Trifinopoulos, B Külekci… - European Spine …, 2016 - Springer
Purpose Surgical site infections represent a major complication of spinal surgery. The
application of lyophilised vancomycin into the wound is reported to significantly decrease …

Neuromuscular scoliosis complication rates from 2004 to 2015: a report from the Scoliosis Research Society Morbidity and Mortality database

D Cognetti, HM Keeny, AF Samdani, JM Pahys… - Neurosurgical …, 2017 - thejns.org
OBJECTIVE Postoperative complications are one of the most significant concerns in
surgeries of the spine, especially in higher-risk cases such as neuromuscular scoliosis …

[HTML][HTML] Surgical site infection prophylaxis and wound management in spine surgery

AJ White, B Fiani, R Jarrah, AA Momin… - Asian Spine …, 2022 - ncbi.nlm.nih.gov
Surgical site infection (SSI) is a potentially devastating complication of spinal surgery that
increases patient morbidity and healthcare costs. SSIs have complex and multifactorial …