Bone remodeling is a continuous process that maintains the homeostasis of the skeletal
system, and it depends on the homeostasis between bone-forming osteoblasts and bone …

Bone morphogenetic proteins (BMPs) constitute the largest subdivision of the transforming
growth factor-β family of ligands. BMPs exhibit widespread utility and pleiotropic, context …

Bone morphogenetic proteins (BMPs) are members of the transforming growth factor-β
family (TGFβ), which signal through hetero-tetrameric complexes of type I and type II …

Bone morphogenetic proteins (BMPs) are cytokines belonging to the transforming growth
factor-β (TGF-β) superfamily. They play multiple functions during development and tissue …

Forkhead transcription factors are essential for diverse processes in early embryonic
development and organogenesis. Foxd1 is required during kidney development and its …

Rendu–Osler–Weber syndrome, also known as hereditary hemorrhagic telangiectasia
(HHT), is an autosomal dominant vascular disorder. Three genes are causally related to …

Human embryonic stem cells (hESCs) have great potential for the repair of damaged
articular cartilage. We developed a serum-free 14-day protocol for hESC differentiation into …

Before the onset of sprouting angiogenesis, the endothelium is prepatterned for the
positioning of tip and stalk cells. Both cell identities are not static, as endothelial cells (ECs) …

In this work we determine the impact of surface density of immobilized BMP-2 on
intracellular signal transduction. We use block copolymer micellar nanolithography to …

ABSTRACT Bone morphogenetic protein 2 (BMP-2) has been known for decades as a
strong osteoinductive factor and for clinical applications is combined solely with collagen as …