Preclinical Evaluation of a Lead Specific Chelator (PSC) Conjugated to Radiopeptides for 203Pb and 212Pb-Based Theranostics
M Li, NJ Baumhover, D Liu, BS Cagle, F Boschetti… - Pharmaceutics, 2023 - mdpi.com
203Pb and 212Pb have emerged as promising theranostic isotopes for image-guided α-
particle radionuclide therapy for cancers. Here, we report a cyclen-based Pb specific …
particle radionuclide therapy for cancers. Here, we report a cyclen-based Pb specific …
Influence of the Molar Activity of 203/212Pb-PSC-PEG2-TOC on Somatostatin Receptor Type 2-Binding and Cell Uptake
M Pretze, E Michler, R Runge, K Wetzig, K Tietze… - Pharmaceuticals, 2023 - mdpi.com
(1) Background: In neuroendocrine tumors (NETs), somatostatin receptor subtype 2 is highly
expressed, which can be targeted by a radioactive ligand such as [177Lu] Lu-1, 4, 7, 10 …
expressed, which can be targeted by a radioactive ligand such as [177Lu] Lu-1, 4, 7, 10 …