Development of biomimetic Phospholipid membrane chromatography for drug discovery: A comprehensive review

J Wang, J Guo, D Xu, L He, JH Qu, Q Wang… - TrAC Trends in …, 2023 - Elsevier
Drug-membrane interactions are important physicochemical properties to be considered at
early drug discovery stage, which can provide deeper understanding of drug …

[HTML][HTML] Recent trends in capillary electrokinetic chromatography with liposomes, lipid aggregates, and lipid emulsions

V Lishchuk, SK Wiedmer - Journal of Chromatography Open, 2024 - Elsevier
The main trends in the use of liposomes or lipid aggregates as pseudostationary phases in
capillary electrokinetic chromatography (EKC) over the past 15 years are reviewed. Due to …

Sphingomyelin ability to act as chiral selector using nanodisc electrokinetic chromatography

WM Penny, CP Palmer - Chemistry and physics of lipids, 2018 - Elsevier
Understanding how stereochemistry affects interactions with cell membranes is important for
effective drug development. Chirality has been shown to greatly effect pharmaceutical …

[图书][B] Determination of lipid bilayer affinities for small molecules using capillary electrophoresis and copolymer-stabilized lipid bilayer nanodiscs

WM Penny - 2018 - search.proquest.com
Electrokinetic chromatography is a variation of capillary electrophoresis that allows for the
separation of nonionic analytes by selective interaction with an ionic pseudostationary …

DEVELOPMENT OF NANODISC AFFINITY CAPILLARY ELECTROPHORESIS TO STUDY THE INTERACTION OF Giα PROTEIN WITH CELL MEMBRANES

BR Emeigh - 2022 - scholarworks.umt.edu
Guanine nucleotide-binding proteins, or G-proteins, are crucial to cell signaling by acting as
molecular switches through interactions with membrane-bound receptors. G-proteins have …