[HTML][HTML] Current mechanistic concepts in ischemia and reperfusion injury
Ischemia-reperfusion injury is associated with serious clinical manifestations, including
myocardial hibernation, acute heart failure, cerebral dysfunction, gastrointestinal …
myocardial hibernation, acute heart failure, cerebral dysfunction, gastrointestinal …
Role of cardiolipin in mitochondrial function and dynamics in health and disease: molecular and pharmacological aspects
G Paradies, V Paradies, FM Ruggiero, G Petrosillo - Cells, 2019 - mdpi.com
In eukaryotic cells, mitochondria are involved in a large array of metabolic and bioenergetic
processes that are vital for cell survival. Phospholipids are the main building blocks of …
processes that are vital for cell survival. Phospholipids are the main building blocks of …
[HTML][HTML] Mitochondrial quality control mechanisms as molecular targets in cardiac ischemia–reperfusion injury
J Wang, H Zhou - Acta Pharmaceutica Sinica B, 2020 - Elsevier
Mitochondrial damage is a critical contributor to cardiac ischemia/reperfusion (I/R) injury.
Mitochondrial quality control (MQC) mechanisms, a series of adaptive responses that …
Mitochondrial quality control (MQC) mechanisms, a series of adaptive responses that …
Melatonin attenuates myocardial ischemia‐reperfusion injury via improving mitochondrial fusion/mitophagy and activating the AMPK‐OPA1 signaling pathways
Y Zhang, Y Wang, J Xu, F Tian, S Hu… - Journal of pineal …, 2019 - Wiley Online Library
Abstract Optic atrophy 1 (OPA1)‐related mitochondrial fusion and mitophagy are vital to
sustain mitochondrial homeostasis under stress conditions. However, no study has …
sustain mitochondrial homeostasis under stress conditions. However, no study has …
Mitophagy, mitochondrial dynamics, and homeostasis in cardiovascular aging
Biological aging is an inevitable and independent risk factor for a wide array of chronic
diseases including cardiovascular and metabolic diseases. Ample evidence has established …
diseases including cardiovascular and metabolic diseases. Ample evidence has established …
Emerging role of mitophagy in cardiovascular physiology and pathology
PE Morales, C Arias-Durán, Y Ávalos-Guajardo… - Molecular aspects of …, 2020 - Elsevier
Healthy mitochondrial function is imperative for most tissues, but especially those with a high
energy demand. Robust evidence linking mitochondrial dysfunction with cardiovascular …
energy demand. Robust evidence linking mitochondrial dysfunction with cardiovascular …
Mitochondrial fission protein 1: emerging roles in organellar form and function in health and disease
UK Ihenacho, KA Meacham, MC Harwig… - Frontiers in …, 2021 - frontiersin.org
Mitochondrial fission protein 1 (Fis1) was identified in yeast as being essential for
mitochondrial division or fission and subsequently determined to mediate human …
mitochondrial division or fission and subsequently determined to mediate human …
MCU Up‐regulation contributes to myocardial ischemia‐reperfusion Injury through calpain/OPA‐1–mediated mitochondrial fusion/mitophagy Inhibition
L Guan, Z Che, X Meng, Y Yu, M Li, Z Yu… - Journal of cellular …, 2019 - Wiley Online Library
Mitochondrial dynamic disorder is involved in myocardial ischemia/reperfusion (I/R) injury.
To explore the effect of mitochondrial calcium uniporter (MCU) on mitochondrial dynamic …
To explore the effect of mitochondrial calcium uniporter (MCU) on mitochondrial dynamic …
ALDH2 attenuates ischemia and reperfusion injury through regulation of mitochondrial fusion and fission by PI3K/AKT/mTOR pathway in diabetic cardiomyopathy
X Tan, Y Chen, S Zou, W Wang, N Zhang… - Free Radical Biology …, 2023 - Elsevier
The function of mitochondrial fusion and fission is one of the important factors causing
ischemia-reperfusion (I/R) injury in diabetic myocardium. Aldehyde dehydrogenase 2 …
ischemia-reperfusion (I/R) injury in diabetic myocardium. Aldehyde dehydrogenase 2 …
Cell death regulation by MAMs: from molecular mechanisms to therapeutic implications in cardiovascular diseases
The endoplasmic reticulum (ER) and mitochondria are interconnected intracellular
organelles with vital roles in the regulation of cell signaling and function. While the ER …
organelles with vital roles in the regulation of cell signaling and function. While the ER …