[HTML][HTML] Fighting antibiotic resistance in hospital-acquired infections: current state and emerging technologies in disease prevention, diagnostics and therapy
E Avershina, V Shapovalova, G Shipulin - Frontiers in microbiology, 2021 - frontiersin.org
Rising antibiotic resistance is a global threat that is projected to cause more deaths than all
cancers combined by 2050. In this review, we set to summarize the current state of antibiotic …
cancers combined by 2050. In this review, we set to summarize the current state of antibiotic …
[HTML][HTML] Efflux pump mediated antimicrobial resistance by staphylococci in health-related environments: challenges and the quest for inhibition
A Dashtbani-Roozbehani, MH Brown - Antibiotics, 2021 - mdpi.com
The increasing emergence of antimicrobial resistance in staphylococcal bacteria is a major
health threat worldwide due to significant morbidity and mortality resulting from their …
health threat worldwide due to significant morbidity and mortality resulting from their …
Inhibitory mechanisms of promising antimicrobials from plant byproducts: A review
M Qian, BB Ismail, Q He, X Zhang… - … Reviews in Food …, 2023 - Wiley Online Library
Plant byproducts and waste present enormous environmental challenges and an
opportunity for valorization and industrial application. Due to consumer demands for natural …
opportunity for valorization and industrial application. Due to consumer demands for natural …
[HTML][HTML] Biochemical and molecular mechanisms of antibiotic resistance in Salmonella spp.
R Chaudhari, K Singh, P Kodgire - Research in Microbiology, 2023 - Elsevier
Salmonella is a diverse Gram-negative bacterium that represents the major disease burden
worldwide. According to WHO, Salmonella is one of the fourth global causes of diarrhoeal …
worldwide. According to WHO, Salmonella is one of the fourth global causes of diarrhoeal …
Tackling multidrug-resistant Staphylococcus aureus by natural products and their analogues acting as NorA efflux pump inhibitors
G Kumar, AK Tudu - Bioorganic & Medicinal Chemistry, 2023 - Elsevier
Staphylococcus aureus (S. aureus) is a pathogen responsible for various community and
hospital-acquired infections with life-threatening complications like bacteraemia …
hospital-acquired infections with life-threatening complications like bacteraemia …
[HTML][HTML] Efflux pump inhibitors in controlling antibiotic resistance: outlook under a heavy metal contamination context
Multi-drug resistance to antibiotics represents a growing challenge in treating infectious
diseases. Outside the hospital, bacteria with the multi-drug resistance (MDR) phenotype …
diseases. Outside the hospital, bacteria with the multi-drug resistance (MDR) phenotype …
Counteracting antibiotic resistance enzymes and efflux pumps
Highlights•Adjuvants potentiate existing antibiotics or combat mechanisms of
resistance.•Probes enable the identification of enzymes that modify tuberculosis …
resistance.•Probes enable the identification of enzymes that modify tuberculosis …
[HTML][HTML] Efflux pumps and microbial biofilm formation
MN Hajiagha, HS Kafil - Infection, Genetics and Evolution, 2023 - Elsevier
Biofilm-related infections are resistant forms of pathogens that are regarded as a medical
problem, particularly due to the spread of multiple drug resistance. One of the factors …
problem, particularly due to the spread of multiple drug resistance. One of the factors …
[HTML][HTML] The Art of War with Pseudomonas aeruginosa: Targeting Mex Efflux Pumps Directly to Strategically Enhance Antipseudomonal Drug Efficacy
Pseudomonas aeruginosa (P. aeruginosa) poses a grave clinical challenge due to its
multidrug resistance (MDR) phenotype, leading to severe and life-threatening infections …
multidrug resistance (MDR) phenotype, leading to severe and life-threatening infections …
Role of bacterial efflux pump proteins in antibiotic resistance across microbial species
Efflux proteins are transporter molecules that actively pump out a variety of substrates,
including antibiotics, from cells to the environment. They are found in both Gram-positive …
including antibiotics, from cells to the environment. They are found in both Gram-positive …