Gut microbiota in phytopharmacology: A comprehensive overview of concepts, reciprocal interactions, biotransformations and mode of actions
P Dey - Pharmacological research, 2019 - Elsevier
The dynamic and delicate interactions amongst intestinal microbiota, metabolome and
metabolism dictates human health and disease. In recent years, our understanding of gut …
metabolism dictates human health and disease. In recent years, our understanding of gut …
[HTML][HTML] Physiological changes due to hepatotoxicity and the protective role of some medicinal plants
HS Abou Seif - Beni-suef University journal of basic and applied …, 2016 - Elsevier
The liver is the largest, important organ and the site for essential biochemical reactions in
the human body. It has the function to detoxify toxic substances and synthesize useful …
the human body. It has the function to detoxify toxic substances and synthesize useful …
Targeting gut barrier dysfunction with phytotherapies: Effective strategy against chronic diseases
P Dey - Pharmacological research, 2020 - Elsevier
The intestinal epithelial layer serves as a physical and functional barrier between the
microbe-rich lumen and immunologically active submucosa; it prevents systemic …
microbe-rich lumen and immunologically active submucosa; it prevents systemic …
Hepatoprotective natural triterpenoids
GB Xu, YH Xiao, QY Zhang, M Zhou, SG Liao - European journal of …, 2018 - Elsevier
Liver diseases are one of the leading causes of death in the world. In spite of tremendous
advances in modern drug research, effective and safe hepatoprotective agents are still in …
advances in modern drug research, effective and safe hepatoprotective agents are still in …
A toxic shrub turned therapeutic: The dichotomy of Nerium oleander bioactivities
R Sharma, S Singh, N Tewari, P Dey - Toxicon, 2023 - Elsevier
Nerium oleander L. is a medicinal plant, used for the treatment of cancers and
hyperglycemia across the world, especially in Indian sub-continent, Turkey, Morocco, and …
hyperglycemia across the world, especially in Indian sub-continent, Turkey, Morocco, and …
Selenium Ameliorates Acetaminophen-Induced Oxidative Stress via MAPK and Nrf2 Pathways in Mice
MC Indumathi, K Swetha, KV Abhilasha… - … Trace Element Research, 2024 - Springer
Overdose of acetaminophen (paracetamol), a widely used non-prescriptive analgesic and
antipyretic medication, is one of the main causes of drug-induced acute liver failure around …
antipyretic medication, is one of the main causes of drug-induced acute liver failure around …
Good girl goes bad: understanding how gut commensals cause disease
P Dey - Microbial Pathogenesis, 2024 - Elsevier
This review examines the complex connection between commensal microbiota and the
development of opportunistic infections. Several underlying conditions, such as metabolic …
development of opportunistic infections. Several underlying conditions, such as metabolic …
Hepatoprotective effect of ethanolic extract of whole plant of Andrographis paniculata against CCl4-induced hepatotoxicity in rats
S Subramaniam, HB Hedayathullah Khan… - Comparative Clinical …, 2015 - Springer
Liver diseases pose a major challenge to international public health. Hepatic damage is
associated with distortion of metabolic functions of the liver. The present study was carried …
associated with distortion of metabolic functions of the liver. The present study was carried …
The role of gut microbiome in chemical-induced metabolic and toxicological murine disease models
P Dey - Life sciences, 2020 - Elsevier
The role of gut microbiome in human health and disease is well established. While evidence-
based pharmacological studies utilize a variety of chemical-induced metabolic and …
based pharmacological studies utilize a variety of chemical-induced metabolic and …
Substance P hinders bile acid-induced hepatocellular injury by modulating oxidative stress and inflammation
D Lee, JS Park, D Kim, HS Hong - Antioxidants, 2022 - mdpi.com
Liver failure is an outcome of chronic liver disease caused by steatohepatitis and cholestatic
injury. This study examined substance P (SP) effect on liver injury due to cholestatic stress …
injury. This study examined substance P (SP) effect on liver injury due to cholestatic stress …