The protein corona from nanomedicine to environmental science
The protein corona spontaneously develops and evolves on the surface of nanoscale
materials when they are exposed to biological environments, altering their physiochemical …
materials when they are exposed to biological environments, altering their physiochemical …
Nanoparticle protein corona: from structure and function to therapeutic targeting
Nanoparticle (NP)-based therapeutics have ushered in a new era in translational medicine.
However, despite the clinical success of NP technology, it is not well-understood how NPs …
However, despite the clinical success of NP technology, it is not well-understood how NPs …
Protein corona: Friend or foe? Co-opting serum proteins for nanoparticle delivery
For systemically delivered nanoparticles to reach target tissues, they must first circulate long
enough to reach the target and extravasate there. A challenge is that the particles end up …
enough to reach the target and extravasate there. A challenge is that the particles end up …
The role of protein corona on nanodrugs for organ-targeting and its prospects of application
S Wang, J Zhang, H Zhou, YC Lu, X Jin, L Luo… - Journal of Controlled …, 2023 - Elsevier
Nowadays, nanodrugs become a hotspot in the high-end medical field. They have the ability
to deliver drugs to reach their destination more effectively due to their unique properties and …
to deliver drugs to reach their destination more effectively due to their unique properties and …
Protein corona formation on lipid nanoparticles negatively affects the NLRP3 inflammasome activation
The interaction between lipid nanoparticles (LNPs) and serum proteins, giving rise to a
unique identification in the form of the protein corona, has been shown to be associated with …
unique identification in the form of the protein corona, has been shown to be associated with …
The Janus of Protein Corona on nanoparticles for tumor targeting, immunotherapy and diagnosis
X Wang, W Zhang - Journal of Controlled Release, 2022 - Elsevier
The therapeutics based on nanoparticles (NPs) are considered as the promising strategy for
tumor detection and treatment. However, one of the most challenges is the adsorption of …
tumor detection and treatment. However, one of the most challenges is the adsorption of …
Nanoparticle-protein corona complex: understanding multiple interactions between environmental factors, corona formation, and biological activity
The surfaces of pristine nanoparticles become rapidly coated by proteins in biological fluids,
forming the so-called protein corona. The corona modifies key physicochemical …
forming the so-called protein corona. The corona modifies key physicochemical …
Biological features of nanoparticles: protein corona formation and interaction with the immune system
S Panico, S Capolla, S Bozzer, G Toffoli, M Dal Bo… - Pharmaceutics, 2022 - mdpi.com
Nanoparticles (NPs) are versatile candidates for nanomedical applications due to their
unique physicochemical properties. However, their clinical applicability is hindered by their …
unique physicochemical properties. However, their clinical applicability is hindered by their …
Nanoparticles in medicine: current status in cancer treatment
Cancer is still a leading cause of deaths worldwide, especially due to those cases
diagnosed at late stages with metastases that are still considered untreatable and are …
diagnosed at late stages with metastases that are still considered untreatable and are …
[HTML][HTML] Protonated-chitosan sponge with procoagulation activity for hemostasis in coagulopathy
Z Huang, D Zhang, L Tong, F Gao, S Zhang, X Wang… - Bioactive Materials, 2024 - Elsevier
Hemostatic materials are essential for managing acute bleeding in medical settings.
Chitosan (CS) shows promise in hemostasis but its underlying mechanism remains …
Chitosan (CS) shows promise in hemostasis but its underlying mechanism remains …