Long-acting formulation strategies for protein and peptide delivery in the treatment of PSED

A Garkal, P Bangar, A Rajput, P Pingale, N Dhas… - Journal of Controlled …, 2022 - Elsevier
The invigoration of protein and peptides in serious eye disease includes age-related
macular degeneration, choroidal neovascularization, retinal neovascularization, and …

[HTML][HTML] Advances in the engineering of the outer blood-retina barrier: From in-vitro modelling to cellular therapy

C Dujardin, W Habeler, C Monville, D Letourneur… - Bioactive Materials, 2024 - Elsevier
The outer blood-retina barrier (oBRB), crucial for the survival and the proper functioning of
the overlying retinal layers, is disrupted in numerous diseases affecting the retina, leading to …

A bioprinted Bruch's membrane for modeling smoke‐induced retinal pigment epithelium degeneration via hybrid membrane printing technology

J Kim, JS Kong, H Kim, Y Jo, DW Cho… - Advanced Healthcare …, 2022 - Wiley Online Library
The retinal pigment epithelium (RPE) not only forms the outer blood‐retinal barrier (oBRB)
but also plays a multifunctional role in the ocular system. The loss of this epithelium leads to …

Acellularized uvea hydrogel as novel injectable platform for cell‐based delivering treatment of retinal degeneration and optimizing retinal organoids inducible system

G Li, S Liu, W Chen, Z Jiang, Y Luo… - Advanced …, 2022 - Wiley Online Library
Replenishing the retina with retinal pigment epithelial (RPE) cells derived from pluripotent
stem cells (PSCs) has great promise for treating retinal degenerative diseases, but it is …

Towards Precision Ophthalmology: The Role of 3D Printing and Bioprinting in Oculoplastic Surgery, Retinal, Corneal, and Glaucoma Treatment

KY Wu, A Tabari, É Mazerolle, SD Tran - Biomimetics, 2024 - mdpi.com
In the forefront of ophthalmic innovation, biomimetic 3D printing and bioprinting technologies
are redefining patient-specific therapeutic strategies. This critical review systematically …

Tissue engineering of the retina: from organoids to microfluidic chips

LF Marcos, SL Wilson, P Roach - Journal of tissue …, 2021 - journals.sagepub.com
Despite advancements in tissue engineering, challenges remain for fabricating functional
tissues that incorporate essential features including vasculature and complex cellular …

Effect of photobiomodulation in suppression of oxidative stress on retinal pigment epithelium

J Kim, JY Won - International Journal of Molecular Sciences, 2022 - mdpi.com
As the world undergoes aging, the number of age-related diseases has increased. One of
them is disease related to retinal pigment epithelium (RPE) degeneration, such as age …

[HTML][HTML] New prospects for retinal pigment epithelium transplantation

VK Gullapalli, MA Zarbin - Asia-Pacific Journal of Ophthalmology, 2022 - Elsevier
Retinal pigment epithelium (RPE) transplants rescue photoreceptors in selected animal
models of retinal degenerative disease. Early clinical studies of RPE transplants as …

Nanomaterials in the diagnosis and treatment of ophthalmic diseases

Y Ma, Z Zhang, Y Yu, X Wang, S Liu, B Sun, Z Cai… - Nano Today, 2024 - Elsevier
The complexity of the human eye structure poses challenges in the diagnosis and treatment
of ocular diseases, especially the low efficiency of ocular drug delivery. With the continuous …

Vitreous levels of vascular endothelial growth factor and platelet-derived growth factor in patients with proliferative Diabetic Retinopathy: a clinical correlation

R Al-Dwairi, T El-Elimat, A Aleshawi, AH Al Sharie… - Biomolecules, 2023 - mdpi.com
Background: The global epidemic status of diabetic retinopathy (DR) and its burden
presents an ongoing challenge to health-care systems. It is of great interest to investigate …