[HTML][HTML] Droplet Hi-C for Fast and Scalable Profiling of Chromatin Architecture in Single Cells

L Chang, Y Xie, B Taylor, Z Wang, J Sun, TR Tan… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Comprehensive analysis of chromatin architecture is crucial for understanding the gene
regulatory programs during development and in disease pathogenesis, yet current methods …

Robust Detection of Gene Amplification in Formalin-Fixed Paraffin-Embedded Samples by Fluorescence In Situ Hybridization

C Gilbreath, Y Peng, S Wu - JoVE (Journal of Visualized Experiments), 2024 - jove.com
Focal gene amplification, such as extrachromosomal DNA (ecDNA), plays an important role
in cancer development and therapy resistance. While sequencing-based methodologies …