The coagulopathy of chronic liver disease

A Tripodi, PM Mannucci - New England Journal of Medicine, 2011 - Mass Medical Soc
The Coagulopathy of Chronic Liver Disease | New England Journal of Medicine Skip to main
content The New England Journal of Medicine homepage Advanced Search SEARCH …

[PDF][PDF] Prevention and management of gastroesophageal varices and variceal hemorrhage in cirrhosis

G Garcia‐Tsao, AJ Sanyal, ND Grace, W Carey… - …, 2007 - Wiley Online Library
These recommendations provide a data-supported approach to the management of patients
with varices and variceal hemorrhage. They are based on the following:(1) formal review …

EASL Clinical Practice Guidelines on prevention and management of bleeding and thrombosis in patients with cirrhosis

E Villa, M Bianchini, A Blasi, A Denys, EG Giannini… - Journal of …, 2022 - Elsevier
The prevention and management of bleeding and thrombosis in patients with cirrhosis
poses several difficult clinical questions. These Clinical Practice Guidelines have been …

[PDF][PDF] Portal hypertensive bleeding in cirrhosis: Risk stratification, diagnosis, and management: 2016 practice guidance by the American Association for the study of …

G Garcia‐Tsao, JG Abraldes, A Berzigotti… - Hepatology, 2017 - Wiley Online Library
This guidance provides a data-supported approach to risk stratification, diagnosis, and
management of patients with cirrhosis and portal hypertension (PH). A guidance document …

Endoscopic diagnosis and management of esophagogastric variceal hemorrhage: European Society of Gastrointestinal Endoscopy (ESGE) Guideline

IM Gralnek, MC Duboc, JC Garcia-Pagan, L Fuccio… - …, 2022 - thieme-connect.com
1 ESGE recommends that patients with compensated advanced chronic liver disease
(ACLD; due to viruses, alcohol, and/or nonobese [BMI< 30 kg/m 2] nonalcoholic …

Early use of TIPS in patients with cirrhosis and variceal bleeding

JC García-Pagán, K Caca, C Bureau… - … England Journal of …, 2010 - Mass Medical Soc
Background Patients with cirrhosis in Child–Pugh class C or those in class B who have
persistent bleeding at endoscopy are at high risk for treatment failure and a poor prognosis …

Safety of recombinant activated factor VII in randomized clinical trials

M Levi, JH Levy, HF Andersen… - New England Journal of …, 2010 - Mass Medical Soc
Background The use of recombinant activated factor VII (rFVIIa) on an off-label basis to treat
life-threatening bleeding has been associated with a perceived increased risk of …

Concepts and controversies in haemostasis and thrombosis associated with liver disease: Proceedings of the 7th International Coagulation in Liver Disease …

NM Intagliata, CK Argo, JG Stine… - Thrombosis and …, 2018 - thieme-connect.com
Patients with acute and chronic liver disease frequently acquire unique changes in
haemodynamic and haemostatic pathways that may result in life-threatening bleeding and …

[PDF][PDF] Evidence of normal thrombin generation in cirrhosis despite abnormal conventional coagulation tests

A Tripodi, F Salerno, V Chantarangkul, M Clerici… - …, 2005 - Wiley Online Library
The role played by coagulation defects in the occurrence of bleeding in cirrhosis is still
unclear. This is partly due to the lack of tests that truly reflect the balance of procoagulant …

[HTML][HTML] Periprocedural management of abnormal coagulation parameters and thrombocytopenia in patients with cirrhosis: guidance from the SSC of the ISTH

LN Roberts, T Lisman, S Stanworth… - Journal of Thrombosis …, 2022 - Elsevier
Prolonged prothrombin time and thrombocytopenia are common in patients with cirrhosis.
These parameters do not reflect the overall hemostatic rebalance or bleeding risk in the …