The role of STATs in ovarian cancer: exploring their potential for therapy
D Standing, E Feess, S Kodiyalam, M Kuehn, Z Hamel… - Cancers, 2023 - mdpi.com
Simple Summary Ovarian cancer remains the deadliest cancer of the female reproductive
system. There is a significant body of evidence that has demonstrated that Signal …
system. There is a significant body of evidence that has demonstrated that Signal …
Small Molecule Therapeutics in the Pipeline Targeting for Triple-Negative Breast Cancer: Origin, Challenges, Opportunities, and Mechanisms of Action
Triple-negative breast cancer (TNBC) cells are devoid of estrogen receptors (ERs),
progesterone receptor (PRs), and human epidermal growth factor receptor 2 (HER2), and it …
progesterone receptor (PRs), and human epidermal growth factor receptor 2 (HER2), and it …
TET2–STAT3–CXCL5 nexus promotes neutrophil lipid transfer to fuel lung adeno-to-squamous transition
Y Xue, Y Chen, S Sun, X Tong, Y Chen… - Journal of Experimental …, 2024 - rupress.org
Phenotypic plasticity is a rising cancer hallmark, and lung adeno-to-squamous transition
(AST) triggered by LKB1 inactivation is significantly associated with drug resistance …
(AST) triggered by LKB1 inactivation is significantly associated with drug resistance …
STAT3 phosphorylation inhibitor Bt354 exhibits anti‐neoplastic activity in glioblastoma multiforme cells
The high mortality rate of glioblastoma multiforme (GBM), a lethal primary brain tumor, is
attributable to postsurgical recurrence. STAT3, an oncogenic protein, is a signal transducer …
attributable to postsurgical recurrence. STAT3, an oncogenic protein, is a signal transducer …
Potential therapeutic targets of the JAK2/STAT3 signaling pathway in triple-negative breast cancer
L Long, X Fei, L Chen, L Yao, X Lei - Frontiers in Oncology, 2024 - frontiersin.org
Triple-negative breast cancer (TNBC) poses a significant clinical challenge due to its
propensity for metastasis and poor prognosis. TNBC evades the body's immune system …
propensity for metastasis and poor prognosis. TNBC evades the body's immune system …
Breast cancer and its therapeutic targets: A comprehensive review
Breast cancer is a common and deadly disease, so there is a constant need for research to
find efficient targets and therapeutic approaches. Breast cancer can be classified on a …
find efficient targets and therapeutic approaches. Breast cancer can be classified on a …