The polymerase chain reaction (PCR) has dramatically altered how molecular studies are
conducted as well as what questions can be asked. In addition to simplifying molecular tasks …

Extremophilic microorganisms are adapted to survive in ecological niches such as at high
temperatures, extremes of pH, high salt concentrations and high pressure. These …

PCR is a technology born of the modern molecular biology era. The enzyme used for PCR,
Taq DNA polymerase, supplied with the 10x buffer, is purchased as a cloned product, and …

Isolation of DNA segments adjacent to known sequences is a tedious task in genome-
related research. We have developed an efficient PCR strategy that overcomes the …

CD4-CD8-(double negative [DN]) alpha/beta T cells are a largely uncharacterized
subpopulation of unknown function. To investigate whether these cells are selected to …

Interleukin-1β (IL-1β) mediates a wide range of immune and inflammatory responses. The
active cytokine is generated by proteolytic cleavage of an inactive precursor. A …

(60) Provisional application No. 60/547,611, filed on Feb. 5,405,783 A 4/1995 Pirrung et al.
24, 2004, provisional application No. 60/546,277. 5,409,811 A 4/1995 Tabor et al. filed on …

(54) METHODS AND APPARATUS FOR 4,962,037 A 10/1990 Jett et al. ANALYZING
POLYNUCLEOTIDE 4,971,903 A 11/1990 Hyman SEQUENCES BY ASYNCHRONOUS …

Adenosine deaminase (ADA) deficiency results in severe combined immunodeficiency, the
first genetic disorder treated by gene therapy. Two different retroviral vectors were used to …

Human mammary cells present on the cell surface a polymorphic epithelial mucin (PEM)
which is developmentally regulated and aberrantly expressed in tumors. PEM carries tumor …