Atrial fibrillation (AF) is the most frequent arrhythmia managed in clinical practice, and it is
linked to an increased risk of death, stroke, and peripheral embolism. The Global Burden of …

Atrial fibrillation (AF) is a common cardiac arrhythmia resulting in increased risk of stroke.
Despite highly heritable etiology, our understanding of the genetic architecture of AF …

Atrial fibrillation (AF) is the most common clinically significant arrhythmia, and it increases
stroke risk. A preventive approach to AF is needed because virtually all treatments such as …

Background There was some evidence that gut microbiota was closely related to
cholelithiasis, but the causal relationship between them remained unclear. In this study, we …

Abstract Background and Aims Low birth weight is a common pregnancy complication,
which has been associated with higher risk of cardiometabolic disease in later life. Prior …

Aims The aim of this study was to use human genetics to investigate the pathogenesis of
sick sinus syndrome (SSS) and the role of risk factors in its development. Methods and …

Introduction cardiovascular disease (CVD) and chronic inflammation are implicated in the
development of frailty. Longitudinal analyses of inflammatory markers, biomarkers of cardiac …

Mendelian randomization (MR) is attracting considerable critical attention. This paper aimed
to explore the characteristics of the publications of MR, to reach an insight in this field and …

Context A genetic predisposition to lower thyrotropin (TSH) levels is associated with
increased atrial fibrillation (AF) risk through undefined mechanisms. Objective Defining the …

Background Height has been associated with many clinical traits but whether such
associations are causal versus secondary to confounding remains unclear in many cases …