The epidermal growth factor receptor (EGFR) is a growth factor receptor that induces cell
differentiation and proliferation upon activation through the binding of one of its ligands. The …

Multiple and diverse cell adhesion molecules take part in intercellular and cell-extracellular
matrix interactions of cancer. Cancer progression is a multi-step process in which some …

E-cadherin is a transmembrane glycoprotein that mediates calcium-dependent, homotypic
cell–cell adhesion and plays a role in maintaining the normal phenotype of epithelial cells …

Compelling experimental evidence exists for a potent invasion suppressor role of the cell‐
cell adhesion molecule E‐cadherin. In addition, a tumour suppressor effect has been …

Several lines of evidence suggest that accumulation of cytoplasmic β-catenin transduces an
oncogenic signal. We show that β-catenin is ubiquitinated and degraded by the proteosome …

Using genome-wide expression profiling of a panel of 27 human mammary cell lines with
different mechanisms of E-cadherin inactivation, we evaluated the relationship between E …

Recent studies show that cadherins and catenins are hormonally regulated and carry out
physiological roles during mammary development but have pathological effects when …

The wnt/β-catenin pathway is important during embryogenesis and carcinogenesis. β-
Catenin interaction with E-cadherin has been shown to be crucial in cell-cell adhesion. We …

Activity-induced changes in adhesion molecules may coordinate presynaptic and
postsynaptic plasticity. Here, we demonstrate that β-catenin, which mediates interactions …

The armadillo gene is a segment polarity gene of Drosophila involved in signal transduction
through wingless. Since the mid-1980s, a growing number of related proteins have been …