Colorectal cancer liver metastases: Genomics and biomarkers with focus on local therapies

Y Kitsel, T Cooke, V Sotirchos, CT Sofocleous - Cancers, 2023 - mdpi.com
Simple Summary Colorectal cancer (CRC) is a leading cause of death among cancer
patients, and the liver is the most common visceral metastatic site. Despite promising …

The importance of optimal thermal ablation margins in colorectal liver metastases: a systematic review and meta-analysis of 21 studies

DD Chlorogiannis, VS Sotirchos, C Georgiades… - Cancers, 2023 - mdpi.com
Simple Summary Colorectal cancer is a significant cause of cancer-related deaths in the US
and the fourth most common malignancy. Percutaneous thermal ablation (TA) is considered …

Ablative margins of colorectal liver metastases using deformable CT image registration and autosegmentation

YM Lin, I Paolucci, CS O'Connor, BM Anderson… - Radiology, 2023 - pubs.rsna.org
Background Confirming ablation completeness with sufficient ablative margin is critical for
local tumor control following colorectal liver metastasis (CLM) ablation. An image-based …

3D margin assessment predicts local tumor progression after ablation of colorectal cancer liver metastases

N Vasiniotis Kamarinos, M Gonen… - International Journal …, 2022 - Taylor & Francis
Objective To determine the feasibility and prognostic value of 3D measuring of the ablation
margins using a dedicated image registration software. Methods This retrospective study …

Real-time split-dose PET/CT-guided ablation improves colorectal liver metastasis detection and ablation zone margin assessments without the need for repeated …

M Zirakchian Zadeh, R Yeh, HS Kunin, AS Kirov… - Cancers, 2022 - mdpi.com
Simple Summary This study showed that adding PET to CT-guided ablation of CLMs can
improve tumor detection for targeting, allowing for repeated tumor visualization for …

Advancements and future outlook of PET/CT-guided interventions

O Dzaye, FH Cornelis, HS Kunin… - Techniques in Vascular …, 2023 - Elsevier
Advancements in minimally invasive technology, coupled with imaging breakthroughs, have
empowered the field of interventional radiology to achieve unparalleled precision in image …

Gradient-based volumetric PET parameters on immediate pre-ablation FDG-PET predict local tumor progression in patients with colorectal liver metastasis treated by …

M Zirakchian Zadeh, R Yeh, AS Kirov, HS Kunin… - CardioVascular and …, 2023 - Springer
Purpose This study aimed to evaluate the optimal method of segmentation of colorectal liver
metastasis (CLM) on immediate pre-ablation PET scans and assess the prognostic value of …

Interstitial photothermal therapy generates durable treatment responses in neuroblastoma

DK Ledezma, PB Balakrishnan… - Advanced …, 2022 - Wiley Online Library
Photothermal therapy (PTT) represents a promising modality for tumor control typically using
infrared light‐responsive nanoparticles illuminated by a wavelength‐matched external laser …

American Radium Society Appropriate Use Criteria for the use of liver‐directed therapies for nonsurgical management of liver metastases: Systematic review and …

CL Hallemeier, N Sharma, C Anker, JE Selfridge… - Cancer, 2023 - Wiley Online Library
The liver is a common site of cancer metastases. Systemic therapy is widely accepted as the
standard treatment for liver metastases (LM), although select patients with liver …

Predictive factors for local recurrence after intraoperative microwave ablation for colorectal liver metastases

Y Wada, Y Takami, T Ryu, Y Uchino, T Kugiyama… - Cancers, 2022 - mdpi.com
Simple Summary The European Society of Medical Oncology and National Comprehensive
Cancer Network guidelines indicate that ablation is recommended as a stand-alone …