Intracellular bacteria in cancer—Prospects and debates

L Schorr, M Mathies, E Elinav, J Puschhof - npj Biofilms and …, 2023 - nature.com
Recent evidence suggests that some human cancers may harbor low-biomass microbial
ecosystems, spanning bacteria, viruses, and fungi. Bacteria, the most-studied kingdom in …

Molecular imaging of bacterial biofilms—a systematic review

SWG Van Hoogstraten, C Kuik, JJC Arts… - Critical reviews in …, 2024 - Taylor & Francis
The formation of bacterial biofilms in the human body and on medical devices is a serious
human health concern. Infections related to bacterial biofilms are often chronic and difficult …

Pseudomonas aeruginosa breaches respiratory epithelia through goblet cell invasion in a microtissue model

AL Swart, BJ Laventie, R Sütterlin, T Junne… - Nature …, 2024 - nature.com
Pseudomonas aeruginosa, a leading cause of severe hospital-acquired pneumonia, causes
infections with up to 50% mortality rates in mechanically ventilated patients. Despite some …

Understanding bacterial pathogenicity: a closer look at the journey of harmful microbes

J Soni, S Sinha, R Pandey - Frontiers in Microbiology, 2024 - frontiersin.org
Bacteria are the most prevalent form of microorganisms and are classified into two
categories based on their mode of existence: intracellular and extracellular. While most …

Evolution of cyclic di-GMP signalling on a short and long term time scale

U Römling, LY Cao, FW Bai - Microbiology, 2023 - microbiologyresearch.org
Diversifying radiation of domain families within specific lineages of life indicates the
importance of their functionality for the organisms. The foundation for the diversifying …

Engineered exosomes as a prospective therapy for diabetic foot ulcers

L Guo, D Xiao, H Xing, G Yang, X Yang - Burns & Trauma, 2024 - academic.oup.com
Diabetic foot ulcer (DFU), characterized by high recurrence rate, amputations and mortality,
poses a significant challenge in diabetes management. The complex pathology involves …

Contribution of intramacrophage stages to Pseudomonas aeruginosa infection outcome in zebrafish embryos: insights from mgtC and oprF mutants

H Hajjar, L Berry, Y Wu, L Touqui, AC Vergunst… - Scientific Reports, 2024 - nature.com
Pseudomonas aeruginosa often colonizes immunocompromised patients, causing acute
and chronic infections. This bacterium can reside transiently inside cultured macrophages …

Evidence for intracellular Pseudomonas aeruginosa

ZJ Resko, RF Suhi, AV Thota, AR Kroken - Journal of Bacteriology, 2024 - Am Soc Microbiol
Pseudomonas aeruginosa is a significant cause of global morbidity and mortality. Although it
is often regarded as an extracellular pathogen toward human cells, numerous investigations …

Intracellular Pseudomonas aeruginosa within the Airway Epithelium of Cystic Fibrosis Lung Tissues

K Malet, E Faure, D Adam, J Donner, L Liu… - American Journal of …, 2024 - atsjournals.org
Rationale: Pseudomonas aeruginosa (Pa) is the major bacterial pathogen colonizing the
airways of adult cystic fibrosis (CF) patients and causes chronic infections that persist …

Intracellular replication of Pseudomonas aeruginosa in epithelial cells requires suppression of the caspase-4 inflammasome

AR Kroken, KA Klein, PS Mitchell, V Nieto, EJ Jedel… - Msphere, 2023 - Am Soc Microbiol
Pathogenesis of Pseudomonas aeruginosa infections can include bacterial survival inside
epithelial cells. Previously, we showed that this involves multiple roles played by the type …