Despite being widely used in reporter technologies, bioluminescent systems are largely
understudied. Of at least forty different bioluminescent systems thought to exist in nature …

Bioluminescence is a ubiquitous imaging modality for visualizing biological processes in
vivo. This technique employs visible light and interfaces readily with most cell and tissue …

Progress toward the development of minimally invasive liquid biopsies of disease is being
bolstered by breakthroughs in the analysis of circulating tumor DNA (ctDNA): DNA released …

The recent availability of highly adaptable engineered nucleic acid binding proteins has
brought about a revolution in the genome-editing field. Now, several studies have …

Firefly luciferase is widely used in molecular biology and bioanalytical systems as a reporter
molecule due to the high quantum yield of the bioluminescence, availability of stable mutant …

Foodborne bacteria are some of the most important human pathogens and can cause many
diseases. In this study, multiplex PCR amplification combined with microchip electrophoresis …

Aptamer-based electrochemical sensors have gained attention in the context of developing
a diagnostic biomarker detection method because of their rapid response, miniaturization …

DNA methylation level at a certain gene region is considered as a new type of biomarker for
diagnosis and its miniaturized and rapid detection system is required for diagnosis. Here we …

Recombinase polymerase amplification (RPA) has been combined with electrochemical
detection for simple and rapid point-of-care testing. However, there are two major …

Direct detection of double-stranded DNA (dsDNA) using zinc finger proteins (ZFPs) is of
great importance in biomedical applications such as identifying pathogens and circulating …