iDNA-ABT: advanced deep learning model for detecting DNA methylation with adaptive features and transductive information maximization

Y Yu, W He, J Jin, G Xiao, L Cui, R Zeng, L Wei - Bioinformatics, 2021 - academic.oup.com
Motivation DNA methylation plays an important role in epigenetic modification, the
occurrence, and the development of diseases. Therefore, identification of DNA methylation …

Research progress in predicting DNA methylation modifications and the relation with human diseases

C Ao, L Gao, L Yu - Current Medicinal Chemistry, 2022 - ingentaconnect.com
DNA methylation is an important mode of regulation in epigenetic mechanisms, and it is one
of the research foci in the field of epigenetics. DNA methylation modification affects a series …

PUResNet: prediction of protein-ligand binding sites using deep residual neural network

J Kandel, H Tayara, KT Chong - Journal of cheminformatics, 2021 - Springer
Background Predicting protein-ligand binding sites is a fundamental step in understanding
the functional characteristics of proteins, which plays a vital role in elucidating different …

DeepTorrent: a deep learning-based approach for predicting DNA N4-methylcytosine sites

Q Liu, J Chen, Y Wang, S Li, C Jia… - Briefings in …, 2021 - academic.oup.com
Abstract DNA N4-methylcytosine (4mC) is an important epigenetic modification that plays a
vital role in regulating DNA replication and expression. However, it is challenging to detect …

[HTML][HTML] Multi-correntropy fusion based fuzzy system for predicting DNA N4-methylcytosine sites

Y Ding, P Tiwari, F Guo, Q Zou - Information Fusion, 2023 - Elsevier
The identification of DNA N4-methylcytosine (4mC) sites is an important field of
bioinformatics. Statistical learning methods and deep learning have been applied in this …

C-loss based higher order fuzzy inference systems for identifying DNA N4-methylcytosine sites

Y Ding, P Tiwari, Q Zou, F Guo… - IEEE Transactions on …, 2022 - ieeexplore.ieee.org
DNA methylation is an epigenetic marker that plays an important role in the biological
processes of regulating gene expression, maintaining chromatin structure, imprinting genes …

A deep multiple kernel learning-based higher-order fuzzy inference system for identifying DNA N4-methylcytosine sites

L Wang, Y Ding, P Tiwari, J Xu, W Lu, K Muhammad… - Information …, 2023 - Elsevier
Abstract N4-methylcytosine (4mC), as a DNA modification, plays a crucial role in epigenetic
regulation. However, the existing experimentation methods for accurately identifying 4mC …

Deep-4mCW2V: A sequence-based predictor to identify N4-methylcytosine sites in Escherichia coli

H Zulfiqar, ZJ Sun, QL Huang, SS Yuan, H Lv, FY Dao… - Methods, 2022 - Elsevier
Abstract N4-methylcytosine (4mC) is a type of DNA modification which could regulate
several biological progressions such as transcription regulation, replication and gene …

CSatDTA: prediction of drug–target binding affinity using convolution model with self-attention

A Ghimire, H Tayara, Z Xuan, KT Chong - International journal of …, 2022 - mdpi.com
Drug discovery, which aids to identify potential novel treatments, entails a broad range of
fields of science, including chemistry, pharmacology, and biology. In the early stages of drug …

A CNN-based RNA N6-methyladenosine site predictor for multiple species using heterogeneous features representation

W Alam, SD Ali, H Tayara, K to Chong - IEEE Access, 2020 - ieeexplore.ieee.org
Post-transcriptional modification such as N6-methyladenosine (m6A) has a crucial role in
the stability and regulation of gene expression. Therefore, the identification of m6A is highly …