Fluoroquinolones structural and medicinal developments (2013–2018): Where are we now?
GARY Suaifan, AAM Mohammed - Bioorganic & medicinal chemistry, 2019 - Elsevier
Fluoroquinolones are considered one of the widely utilized antibiotics, specifically, with the
recent development of newer generations such as moxifloxacin, delafloxacin and …
recent development of newer generations such as moxifloxacin, delafloxacin and …
Fluoroquinolones' biological activities against laboratory microbes and cancer cell lines
Development of novel derivatives to rein in and fight bacteria have never been more
demanding, as microbial resistance strains are alarmingly increasing. A multitude of new …
demanding, as microbial resistance strains are alarmingly increasing. A multitude of new …
Discovery of novel arylethenesulfonyl fluorides as potential candidates against methicillin-resistant of Staphylococcus aureus (MRSA) for overcoming multidrug …
The multidrug-resistant Staphylococcus aureus (MRSA) is one of the most prevalent human
pathogens involved in many minor to major disease burdens throughout the world. Inhibition …
pathogens involved in many minor to major disease burdens throughout the world. Inhibition …
Optimization Rules for SARS-CoV-2 Mpro Antivirals: Ensemble Docking and Exploration of the Coronavirus Protease Active Site
SV Stoddard, SD Stoddard, BK Oelkers, K Fitts… - Viruses, 2020 - mdpi.com
Coronaviruses are viral infections that have a significant ability to impact human health.
Coronaviruses have produced two pandemics and one epidemic in the last two decades …
Coronaviruses have produced two pandemics and one epidemic in the last two decades …
Synthesis, characterization, PXRD studies, and theoretical calculation of the effect of gamma irradiation and antimicrobial studies on novel Pd (II), Cu (II), and Cu (I) …
The main objective of this study is to synthesize and characterize of a new three complexes
of Pd (II), Cu (II), and Cu (I) metal ions with novel ligand ((Z)-2-(phenylamino)-N'-(thiophen-2 …
of Pd (II), Cu (II), and Cu (I) metal ions with novel ligand ((Z)-2-(phenylamino)-N'-(thiophen-2 …
4-Bromo-4'-chloro pyrazoline analog of curcumin augmented anticancer activity against human cervical cancer, HeLa cells: in silico-guided analysis, synthesis, and in …
Inspired by the synergistic effects of hetero-aromatic scaffolds on curcumin, a novel array of
pyrazoline substituted curcumin analogs was designed. Multi-scale computational studies …
pyrazoline substituted curcumin analogs was designed. Multi-scale computational studies …
Biosynthesis, characterization, and antimicrobial effect of silver nanoparticles obtained using Lavandula × intermedia
Abstract The use..... of aqueous leaf extract of Lavandula× intermedia for biosynthesis of
silver nanoparticles (AgNPs) is presented. The plant extract was obtained by boiling dried …
silver nanoparticles (AgNPs) is presented. The plant extract was obtained by boiling dried …
Synthesis of Ester‐Linked Ursolic Acid‐Based Hybrid Compounds: Potential Antibacterial and Anticancer Agents
The molecular hybridization of two or more drugs into a single molecule is an effective drug
design approach to reduce pill burden and improve patient treatment adherence. Ursolic …
design approach to reduce pill burden and improve patient treatment adherence. Ursolic …
Synthesis, characterization, thermal, antimicrobial and antioxidant studies of some transition metal dithiocarbamates
DC Onwudiwe, AC Ekennia - Research on Chemical Intermediates, 2017 - Springer
Metal dithiocarbamate complexes of Co (II)[1], Cu (II)[2], Mn (II)[3], Cr (III)[4], and Pd (II)[5]
have been synthesized using sodium N-ethyl-N-phenyldithiocarbamate (NaL). The …
have been synthesized using sodium N-ethyl-N-phenyldithiocarbamate (NaL). The …
In Vitro and In Silico Toxicological Properties of Natural Antioxidant Therapeutic Agent Azima tetracantha. LAM
Plant-derived antioxidants are a large group of natural products with the capacity to reduce
radical-scavenging. Due to their potent therapeutic and preventive actions, these …
radical-scavenging. Due to their potent therapeutic and preventive actions, these …