Emerging anticancer potential and mechanisms of snake venom toxins: A review

X Guo, Y Fu, J Peng, Y Fu, S Dong, RB Ding… - International Journal of …, 2024 - Elsevier
Animal-derived venom, like snake venom, has been proven to be valuable natural resources
for the drug development. Previously, snake venom was mainly investigated in its …

[HTML][HTML] Anticancer activity a of caspian cobra (Naja naja oxiana) snake venom in human cancer cell lines via induction of apoptosis

K Ebrahim, H Vatanpour, A Zare… - Iranian journal of …, 2016 - ncbi.nlm.nih.gov
Cancer is the leading cause of death worldwide. Current anticancer drugs involve various
toxic side effects; efforts are ongoing to develop new anticancer agents especially from the …

Antitumor effects of snake venom chemically modified Lys49 phospholipase A2-like BthTX-I and a synthetic peptide derived from its C-terminal region

LC Gebrim, S Marcussi, DL Menaldo, CSR de Menezes… - Biologicals, 2009 - Elsevier
The present work evaluates both in vitro and in vivo antitumor activity of BPB-modified BthTX-
I and its cationic synthetic peptide derived from the 115–129 C-terminal region. BPB-BthTX-I …

Comparative Study of Structure and Activity of Cytotoxins from Venom of the Cobras Naja oxiana, Naja kaouthia, and Naja haje

AV Feofanov, GV Sharonov, MA Dubinnyi… - Biochemistry …, 2004 - Springer
Cytotoxins are positively charged polypeptides that constitute about 60% of all proteins in
cobra venom; they have a wide spectrum of biological activities. By CD spectroscopy …

Daboialectin, a C-type lectin from Russell's viper venom induces cytoskeletal damage and apoptosis in human lung cancer cells in vitro

J Pathan, S Mondal, A Sarkar, D Chakrabarty - Toxicon, 2017 - Elsevier
Abstract 'Daboialectin', a low molecular weight C-type lectin (18.5 kDa) isolated from
Russell's viper venom showed cytotoxic effects on human broncho-alveolar carcinoma …

Effects of spider Macrothele raven venom on cell proliferation and cytotoxicity in HeLa cells

L Gao, B Shan, J Chen, J Liu, D Song… - Acta Pharmacologica …, 2005 - nature.com
Aim: To examine the effect of venom from the spider Macrothele raven on cell proliferation
and cytotoxicity in human cervical carcinoma, HeLa cells. Methods: Morphological and …

Regression of murine Ehrlich ascites carcinoma using synthesized cobalt complex

EA Saad, MM Hassanien, HA El-Mezayen… - …, 2017 - pubs.rsc.org
Cisplatin as a chief chemotherapy has nephro-toxicity and so we have tried to develop a
novel antitumor drug based on a combination of cobalt metal ion with an organic moiety. The …

A heat stable protein toxin (drCT-I) from the Indian Viper (Daboia russelli russelli) venom having antiproliferative, cytotoxic and apoptotic activities

A Gomes, SR Choudhury, A Saha, R Mishra, B Giri… - Toxicon, 2007 - Elsevier
A heat stable 7.2 kDa protein toxin (drCT-I) has been purified and crystallized from Indian
Daboia russelli russelli venom (Roy Choudhury et al., 2006. Acta Cryst. F Struct Biol Cryst …

Antitumor and antioxidant role of Chrysaora quinquecirrha (sea nettle) nematocyst venom peptide against ehrlich ascites carcinoma in Swiss Albino mice

E Balamurugan, BV Reddy, VP Menon - Molecular and cellular …, 2010 - Springer
This investigation aims to evaluate the antitumor and antioxidant potential of Chrysaora
quinquecirrha (sea nettle) nematocyst venom on Ehrlich ascites carcinoma (EAC) tumor …

Effect of spider venom on cell apoptosis and necrosis rates in MCF-7 cells

L Gao, S Yu, Y Wu, B Shan - DNA and cell biology, 2007 - liebertpub.com
The purpose of this study was to examine the effects of antitumor activity of the venom from
the spider Macrothele raven (Araneae, Hexathelidae) on the human breast carcinoma cell …