Neuropathic pain conditions including neuropathic orofacial pain (NOP) are difficult to treat.
Contemporary therapeutic agents for neuropathic pain are often ineffective in relieving pain …

The use of cannabis preparations has steadily increased. Although cannabis was
traditionally assumed to only have mild vegetative side effects, it has become evident in …

The larynx and associated laryngopharyngeal regions are innervated by the superior
laryngeal nerve (SLN) and are highly reflexogenic. Transient receptor potential (TRP) …

Oropharyngeal dysphagia, or difficulty in swallowing, is a major health problem that can lead
to serious complications, such as pulmonary aspiration, malnutrition, dehydration, and …

Swallow-breathing coordination safeguards the lower airways from tracheal aspiration of
bolus material as it moves through the pharynx into the esophagus. Impaired movements of …

Endozepines are endogenous ligands for the benzodiazepine receptors and also target a
still unidentified GPCR. The endozepine octadecaneuropeptide (ODN), an endoproteolytic …

Trichothecenes are toxic metabolites produced by fungi that constitute a worldwide hazard
for agricultural production and both animal and human health. More than 40 countries have …

We examined the role of TRPA1s in triggering the swallowing reflex. TRPA1s predominantly
localized on thin nerve fibers and fibroblast-like cells in swallowing-related regions and on …

Background Cannabinoids have been traditionally used for the treatment of gastrointestinal
(GI) symptoms, but the associated central effects, through cannabinoid‐1 receptors (CB 1R) …

The endocannabinoid system (ECS) primarily consists of cannabinoid receptors (CBRs),
endogenous ligands, and enzymes for endocannabinoid biosynthesis and inactivation …