Bladder cancer (BC) is the tenth most common cancer worldwide with a high recurrence
rate, morbidity and mortality. Therefore, chemoprevention and improved treatment of BC are …

Vitamin A has long been associated with bladder cancer, and many exogenous vitamin A
supplements, vitamin A derivatives, and synthetic drugs have been investigated over the …

β-carotene is known to have pharmacological effects such as anti-inflammatory, antioxidant,
and anti-tumor properties. However, its main mechanism and related signaling pathways in …

Enhancer of zeste homolog 2 (EZH2) is a core component of polycomb repressive complex
2 that plays a vital role in transcriptional repression of gene expression. Conditional ablation …

Bladder cancer (BCa) is the most common genitourinary malignancy, with a high global
incidence and recurrence rate that is paired with an increasing caregiver burden and higher …

Urinary bladder cancer can be treated by intravesical application of therapeutic agents, but
the specific targeting of cancer urothelial cells and the endocytotic pathways of the agents …

The exploration of targeted therapy has proven to be a highly promising avenue in the realm
of drug development research. The human body generates a substantial amount of free …

Urinary bladder cancer is the tenth most common cancer worldwide with high morbidity and
mortality. The majority of bladder cancers are urothelial carcinomas. More than half are …

The urothelium, an epithelium of the urinary bladder, primarily functions as blood-urine
permeability barrier. The urothelium has a very slow turnover under normal conditions but is …

Around 3% of new cancer diagnoses and 2% of all cancer deaths every year are caused by
urinary bladder cancer (BC). This indicates a great need for intensive studying of BC by …