Prolonged microgravity exposure during long-duration spaceflight (LDSF) produces unusual
physiologic and pathologic neuro-ophthalmic findings in astronauts. These microgravity …

The neuro-ocular effects of long-duration spaceflight have been termed Spaceflight
Associated Neuro-Ocular Syndrome (SANS) and are a potential challenge for future, human …

Papilledema is optic nerve head edema secondary to raised intracranial pressure (ICP). It is
distinct from other causes of optic disk edema in that visual function is usually normal in the …

Interesting novel and somewhat perplexing physiologic and pathologic neuro-ocular
findings have been documented in astronauts during and after long duration space flight …

Importance Optic disc edema develops in astronauts during long-duration spaceflight and is
a risk for all future astronauts during spaceflight. Having a ground-based analogue of …

Astronauts who undergo prolonged periods of spaceflight may develop a unique
constellation of neuro-ocular findings termed Spaceflight Associated Neuro-Ocular …

New and unique physiologic and pathologic systemic and neuro-ocular responses have
been documented in astronauts during and after long-duration space flight. Although the …

Importance During long-duration spaceflights, nearly all astronauts exhibit some change in
ocular structure within the spectrum of spaceflight-associated neuro-ocular syndrome …

Astronauts in microgravity experience multi-system deconditioning, impacting their inflight
efficiency and inducing dysfunctions upon return to Earth gravity. To fill the sex gap of …

Spaceflight associated neuro-ocular syndrome (SANS) refers to a unique collection of neuro-
ophthalmic clinical and imaging findings observed in astronauts after long-duration …