It is well known that adipokines are endocrine factors that are mainly secreted by white
adipose tissue. Their central role in energy metabolism is currently accepted. More recently …

Apelin has been isolated from the bovine stomach extracts as an endogenous ligand of the
previously orphan receptor APJ. Expression of the apelinergic system (apelin and APJ) was …

Background Neuroinflammation and oxidative stress play important roles in early brain
injury following subarachnoid hemorrhage (SAH). This study is the first to show that …

Type 2 diabetes mellitus is one of the most prevalent metabolic diseases presenting with
systemic pathologies, including reproductive disorders in male diabetic patients. However …

Apelin is an endogenous ligand of the apelin receptor (APJ), a seven-transmembrane G
protein-coupled receptor. Apelin/APJ system has a wide tissue distribution in the brain as …

Apelin (APLN) is a recently discovered adipokine involved in the regulation of various
metabolic functions. Its receptor, APLNR, is expressed in reproductive tissues, however, its …

Apelin was thought to be an adipocyte-specific hormone, but recent studies indicate a link
between apelin and female reproductive function. Using real-time PCR, immunoblotting …

Polycystic ovary syndrome (PCOS) is an endocrinopathy, and it accounts for 75% of non-
ovulatory infertile in women of childbearing age. It is clear that obesity, insulin resistance …

Neuronal apoptosis plays important roles in the early brain injury after subarachnoid
hemorrhage (SAH). This study first showed that inhibition of activating transcription factor 6 …

From mammals to fish, reproduction is driven by luteinizing hormone (LH) and follicle-
stimulating hormone (FSH) temporally secreted from the pituitary gland. Teleost fish are an …