This review gives an updated picture of each class of phenolic compounds and their
properties. The most common classification implies the subdivision of phenolics in two main …

Monoamine oxidases (MAO-A and MAO-B) are mammalian flavoenzyme, which catalyze the
oxidative deamination of several neurotransmitters like norepinephrine, dopamine, tyramine …

Recently, deep generative models have revealed itself as a promising way of performing de
novo molecule design. However, previous research has focused mainly on generating …

Oxygen heterocycles are the second most common type of heterocycles that appear as
structural components of US Food and Drug Administration (FDA) approved …

Methods to functionalize arenes and heteroarenes in a site-selective manner are highly
sought after for rapidly constructing value-added molecules of medicinal, agrochemical, and …

Herein, we present a practical strategy for the direct construction of structurally diverse
trifluoromethyl carbinol-containing compounds, especially CF3-substituted tertiary alcohol …

Abstract α-Glucosidase enzyme inhibition is an effective therapeutic decorum in the
treatment of type 2 diabetes mellitus. Since 1990, three α-glucosidase inhibitors are known …

Accomplished herein is a rearrangement strategy for the highly efficient assembly of
synthetically cumbersome while medicinally significant 2-amino-3-formyl chromones via …

The drug repurposing of known approved drugs (eg, lopinavir/ritonavir) has failed to treat
SARS-CoV-2-infected patients. Therefore, it is important to generate new chemical entities …

Agarwood is a resinous part of the non-timber Aquilaria tree, which is a highly valuable
product for medicine and fragrance purposes. To protect the endangered Aquilaria species …