Regulatory logic underlying diversification of the neural crest

ML Martik, ME Bronner - Trends in Genetics, 2017 - cell.com
The neural crest is a transient, multipotent population of cells that arises at the border of the
developing nervous system. After closure of the neural tube, these cells undergo an …

Development, diversity, and neurogenic capacity of enteric glia

W Boesmans, A Nash, KR Tasnády, W Yang… - Frontiers in Cell and …, 2022 - frontiersin.org
Enteric glia are a fascinating population of cells. Initially identified in the gut wall as the
“support” cells of the enteric nervous system, studies over the past 20 years have unveiled a …

CellTag Indexing: genetic barcode-based sample multiplexing for single-cell genomics

C Guo, W Kong, K Kamimoto, GC Rivera-Gonzalez… - Genome biology, 2019 - Springer
High-throughput single-cell assays increasingly require special consideration in
experimental design, sample multiplexing, batch effect removal, and data interpretation …

An atlas of neural crest lineages along the posterior developing zebrafish at single-cell resolution

AGA Howard IV, PA Baker, R Ibarra-García-Padilla… - Elife, 2021 - elifesciences.org
Neural crest cells (NCCs) are vertebrate stem cells that give rise to various cell types
throughout the developing body in early life. Here, we utilized single-cell transcriptomic …

Enteric glia as a source of neural progenitors in adult zebrafish

S McCallum, Y Obata, E Fourli, S Boeing, CJ Peddie… - Elife, 2020 - elifesciences.org
The presence and identity of neural progenitors in the enteric nervous system (ENS) of
vertebrates is a matter of intense debate. Here, we demonstrate that the non-neuronal ENS …

Early chromatin shaping predetermines multipotent vagal neural crest into neural, neuronal and mesenchymal lineages

ITC Ling, T Sauka-Spengler - Nature Cell Biology, 2019 - nature.com
The enteric nervous system (ENS) predominantly originates from vagal neural crest (VNC)
cells that emerge from the caudal hindbrain, invade the foregut and populate the …

Gut feelings: Studying enteric nervous system development, function, and disease in the zebrafish model system

J Ganz - Developmental Dynamics, 2018 - Wiley Online Library
The enteric nervous system (ENS) is the largest part of the peripheral nervous system and is
entirely neural crest–derived. It provides the intrinsic innervation of the gut, controlling …

[HTML][HTML] Cell-type-specific responses to the microbiota across all tissues of the larval zebrafish

MS Massaquoi, GL Kong, D Chilin-Fuentes, JS Ngo… - Cell reports, 2023 - cell.com
Animal development proceeds in the presence of intimate microbial associations, but the
extent to which different host cells across the body respond to resident microbes remains to …

Zebrafish: a model organism for studying enteric nervous system development and disease

LE Kuil, RK Chauhan, WW Cheng… - Frontiers in Cell and …, 2021 - frontiersin.org
The Enteric Nervous System (ENS) is a large network of enteric neurons and glia that
regulates various processes in the gastrointestinal tract including motility, local blood flow …

The gut-brain-microbiome axis and its link to autism: emerging insights and the potential of zebrafish models

DM James, EA Davidson, J Yanes… - Frontiers in cell and …, 2021 - frontiersin.org
Research involving autism spectrum disorder (ASD) most frequently focuses on its key
diagnostic criteria: restricted interests and repetitive behaviors, altered sensory perception …