Role of Efflux Pumps on Antimicrobial Resistance in Pseudomonas aeruginosa
AB Lorusso, JA Carrara, CDN Barroso, FF Tuon… - International journal of …, 2022 - mdpi.com
Antimicrobial resistance is an old and silent pandemic. Resistant organisms emerge in
parallel with new antibiotics, leading to a major global public health crisis over time …
parallel with new antibiotics, leading to a major global public health crisis over time …
Counteracting antibiotic resistance enzymes and efflux pumps
Highlights•Adjuvants potentiate existing antibiotics or combat mechanisms of
resistance.•Probes enable the identification of enzymes that modify tuberculosis …
resistance.•Probes enable the identification of enzymes that modify tuberculosis …
Outer Membrane Proteins and Efflux Pumps Mediated Multi-Drug Resistance in Salmonella: Rising Threat to Antimicrobial Therapy
Despite colossal achievements in antibiotic therapy in recent decades, drug-resistant
pathogens have remained a leading cause of death and economic loss globally. One such …
pathogens have remained a leading cause of death and economic loss globally. One such …
The Art of War with Pseudomonas aeruginosa: Targeting Mex Efflux Pumps Directly to Strategically Enhance Antipseudomonal Drug Efficacy
Pseudomonas aeruginosa (P. aeruginosa) poses a grave clinical challenge due to its
multidrug resistance (MDR) phenotype, leading to severe and life-threatening infections …
multidrug resistance (MDR) phenotype, leading to severe and life-threatening infections …
Wearable adjunct ozone and antibiotic therapy system for treatment of Gram-negative dermal bacterial infection
The problematic combination of a rising prevalence of skin and soft tissue infections and the
growing rate of life-threatening antibiotic resistant infections presents an urgent, unmet need …
growing rate of life-threatening antibiotic resistant infections presents an urgent, unmet need …
Halogenated antimicrobial agents to combat drug-resistant pathogens
Antimicrobial resistance presents us with a potential global crisis as it undermines the
abilities of conventional antibiotics to combat pathogenic microbes. The history of …
abilities of conventional antibiotics to combat pathogenic microbes. The history of …
Efflux pump inhibitory potential of indole derivatives as an arsenal against norA over-expressing Staphylococcus aureus
NorA, an extensively studied efflux pump in Staphylococcus aureus, has been connected to
fluoroquinolone, antiseptic, and disinfection resistance. Several studies have also …
fluoroquinolone, antiseptic, and disinfection resistance. Several studies have also …
Boosting the Antibacterial Activity of Azithromycin on Multidrug-Resistant Escherichia coli by Efflux Pump Inhibition Coupled with Outer Membrane Permeabilization …
F Al-Marzooq, A Ghazawi, L Daoud, S Tariq - International journal of …, 2023 - mdpi.com
The global spread of multidrug-resistant (MDR) bacteria increases the demand for the
discovery of new antibiotics and adjuvants. Phenylalanine-arginine β-naphthylamide …
discovery of new antibiotics and adjuvants. Phenylalanine-arginine β-naphthylamide …
Nanocomposites against Pseudomonas aeruginosa biofilms: Recent advances, challenges, and future prospects
Pseudomonas aeruginosa is an opportunistic bacterial pathogen that causes life-
threatening and persistent infections in immunocompromised patients. It is the culprit behind …
threatening and persistent infections in immunocompromised patients. It is the culprit behind …
Biocompatibility and Safety Assessment of Combined Topical Ozone and Antibiotics for Treatment of Infected Wounds
A Roth, A Krishnakumar, RR McCain… - ACS Biomaterials …, 2023 - ACS Publications
Wound infections with antibiotic-resistant bacteria, particularly the Gram-negative strains,
pose a substantial health risk for patients with limited treatment options. Recently topical …
pose a substantial health risk for patients with limited treatment options. Recently topical …