Reactive oxygen species (ROS) scavenging biomaterials for anti-inflammatory diseases: From mechanism to therapy

J Liu, X Han, T Zhang, K Tian, Z Li, F Luo - Journal of Hematology & …, 2023 - Springer
Inflammation is a fundamental defensive response to harmful stimuli, but the overactivation
of inflammatory responses is associated with most human diseases. Reactive oxygen …

Reactive oxygen species (ROS)-responsive biomaterials mediate tissue microenvironments and tissue regeneration

Y Yao, H Zhang, Z Wang, J Ding, S Wang… - Journal of Materials …, 2019 - pubs.rsc.org
Reactive oxygen species (ROS) have been considered the pivotal signaling molecules in
many physiological processes, and are usually overproduced in various inflammatory …

ROS-triggered self-disintegrating and pH-responsive astaxanthin nanoparticles for regulating the intestinal barrier and colitis

X Zhang, X Zhao, Z Hua, S Xing, J Li, S Fei, M Tan - Biomaterials, 2023 - Elsevier
Smart delivery systems with stimuli-responsive capability are able to improve the
bioaccessibility through increasing the solubility, physicochemical stability and …

Amelioration of post-traumatic osteoarthritis via nanoparticle depots delivering small interfering RNA to damaged cartilage

SK Bedingfield, JM Colazo, F Yu, DD Liu… - Nature biomedical …, 2021 - nature.com
The progression of osteoarthritis is associated with inflammation triggered by the enzymatic
degradation of extracellular matrix in injured cartilage. Here we show that a locally injected …

Polymeric Nanoparticles for Drug Delivery

MA Beach, U Nayanathara, Y Gao, C Zhang… - Chemical …, 2024 - ACS Publications
The recent emergence of nanomedicine has revolutionized the therapeutic landscape and
necessitated the creation of more sophisticated drug delivery systems. Polymeric …

[HTML][HTML] Intra-articular nanoparticles based therapies for osteoarthritis and rheumatoid arthritis management

J Wen, H Li, H Dai, S Hua, X Long, H Li, S Ivanovski… - Materials Today Bio, 2023 - Elsevier
Osteoarthritis (OA) and rheumatoid arthritis (RA) are chronic and progressive inflammatory
joint diseases that affect a large population worldwide. Intra-articular administration of …

Anti-oxidant activity reinforced reduced graphene oxide/alginate microgels: mesenchymal stem cell encapsulation and regeneration of infarcted hearts

G Choe, SW Kim, J Park, J Park, S Kim, YS Kim, Y Ahn… - Biomaterials, 2019 - Elsevier
Mesenchymal stem cell (MSC) transplantation is promising for repairing heart tissues post
myocardial infarction (MI). In particular, paracrine effects of the transplanted MSCs have …

Reactive oxygen species (ROS)-responsive biomaterials for the treatment of bone-related diseases

X Ren, H Liu, X Wu, W Weng, X Wang… - … in Bioengineering and …, 2022 - frontiersin.org
Reactive oxygen species (ROS) are the key signaling molecules in many physiological
signs of progress and are associated with almost all diseases, such as atherosclerosis …

Reactive oxygen species scavenging with a biodegradable, thermally responsive hydrogel compatible with soft tissue injection

Y Zhu, Y Matsumura, M Velayutham, LM Foley… - Biomaterials, 2018 - Elsevier
Tissue damage and the impairment of regenerative processes by excessive reactive oxygen
species (ROS) contributes to the pathogenesis of various diseases in soft tissues including …

Chondroitin sulfate microspheres anchored with drug-loaded liposomes play a dual antioxidant role in the treatment of osteoarthritis

Y He, M Sun, J Wang, X Yang, C Lin, L Ge, C Ying… - Acta Biomaterialia, 2022 - Elsevier
Reactive oxygen species (ROS) play a critical role in the pathogenesis of osteoarthritis. The
injection of a single antioxidant drug is characterized by low drug utilization and short …