Molecular mechanism of diabetic neuropathy and its pharmacotherapeutic targets

S Dewanjee, S Das, AK Das, N Bhattacharjee… - European journal of …, 2018 - Elsevier
Diabetic neuropathy is regarded as one of the most debilitating outcomes of diabetes
mellitus and may cause pain, decreased motility, and even amputation. Diabetic neuropathy …

Diabetic neuropathies

AI Vinik - Atlas of Diabetes: Fourth Edition, 2011 - Springer
Diabetic neuropathy is not a single entity but rather a number of different syndromes, each
with a range of clinical and subclinical manifestations. According to the San Antonio …

Antioxidant strategies in the management of diabetic neuropathy

AB Oyenihi, AO Ayeleso, E Mukwevho… - BioMed research …, 2015 - Wiley Online Library
Chronic hyperglycaemia (an abnormally high glucose concentration in the blood) resulting
from defects in insulin secretion/action, or both, is the major hallmark of diabetes in which it …

[HTML][HTML] A comprehensive review of neuronal changes in diabetics

R Luna, RT Manjunatha, B Bollu, S Jhaveri… - Cureus, 2021 - ncbi.nlm.nih.gov
There has been an exponential rise in diabetes mellitus (DM) cases on a global scale.
Diabetes affects almost every system of the body, and the nervous system is no exception …

Role of oxidative stress in diabetes-induced complications and their management with antioxidants

H Singh, R Singh, A Singh, H Singh… - … of Physiology and …, 2023 - Taylor & Francis
Diabetes mellitus (DM) is a huge global health issue and one of the most studied diseases,
with a large global prevalence. Oxidative stress is a cytotoxic consequence of the excessive …

[HTML][HTML] Drug repurposing–A search for novel therapy for the treatment of diabetic neuropathy

A Paul, M Kumar, P Das, N Guha, M Rudrapal… - Biomedicine & …, 2022 - Elsevier
Diabetic neuropathy is a chronic complication to metabolic disorder, diabetes mellitus. Till
date, diagnosis and treatment of diabetic neuropathy remain elusive with challenges …

Metabolic syndrome and neuroprotection

M Etchegoyen, MH Nobile, F Baez… - Frontiers in …, 2018 - frontiersin.org
Introduction: Over the years the prevalence of metabolic syndrome (MetS) has drastically
increased in developing countries as a major byproduct of industrialization. Many factors …

New horizons in diabetic neuropathies: an updated review on their pathology, diagnosis, mechanism, screening techniques, pharmacological, and future approaches

N Aziz, B Dash, P Wal, P Kumari… - Current Diabetes …, 2024 - ingentaconnect.com
Background: One of the largest problems for global public health is diabetes mellitus (DM)
and its micro and macrovascular consequences. Although prevention, diagnosis, and …

QSAR and flexible docking studies of some aldose reductase inhibitors obtained from natural origin

SV Jain, KS Bhadoriya, SB Bari - Medicinal Chemistry Research, 2012 - Springer
Abstract Treatment of diabetic complications with inhibitors of aldose reductase (AR) is
biochemically attractive because the AR initiated accumulation of sorbitol, and its resulting …

[PDF][PDF] Anti hyperglycemic, anti oxidant, anti hyperlipidemic & nephroprotective effect of Stevioside in diabetic rats

A Scaria, JV Kamath, M Chakraborty - International Journal of …, 2017 - researchgate.net
Objective: The present study aimed to evaluate in vivo the antihyperglycemic, anti oxidant,
antihyperlipidemic and nephroprotective effects of Stevioside against Alloxan induced …