The Epidemiology and Pathogenesis and Treatment of Pseudomonas aeruginosa Infections: An Update

D Reynolds, M Kollef - Drugs, 2021 - Springer
Pseudomonas aeruginosa is a Gram-negative bacterial pathogen that is a common cause of
nosocomial infections, particularly pneumonia, infection in immunocompromised hosts, and …

Improving lung health in low-income and middle-income countries: from challenges to solutions

J Meghji, K Mortimer, A Agusti, BW Allwood, I Asher… - The Lancet, 2021 - thelancet.com
Low-income and middle-income countries (LMICs) bear a disproportionately high burden of
the global morbidity and mortality caused by chronic respiratory diseases (CRDs), including …

[HTML][HTML] British Thoracic Society Guideline for bronchiectasis in adults

AT Hill, AL Sullivan, JD Chalmers, A De Soyza… - Thorax, 2019 - thorax.bmj.com
CT scanning can also aid in identifying an aetiology of bronchiectasis eg Allergic
bronchopulmonary aspergillosis (ABPA), Non-tuberculous mycobacteria (NTM), primary …

European Respiratory Society guidelines for the management of adult bronchiectasis

E Polverino, PC Goeminne… - European …, 2017 - Eur Respiratory Soc
Bronchiectasis in adults is a chronic disorder associated with poor quality of life and frequent
exacerbations in many patients. There have been no previous international guidelines. The …

Advances in bronchiectasis: endotyping, genetics, microbiome, and disease heterogeneity

PA Flume, JD Chalmers, KN Olivier - The Lancet, 2018 - thelancet.com
Bronchiectasis is characterised by pathological dilation of the airways. More specifically, the
radiographic demonstration of airway enlargement is the common feature of a …

Neutrophil extracellular traps, disease severity, and antibiotic response in bronchiectasis: an international, observational, multicohort study

HR Keir, A Shoemark, AJ Dicker, L Perea… - The lancet Respiratory …, 2021 - thelancet.com
Background Bronchiectasis is predominantly a neutrophilic inflammatory disease. There are
no established therapies that directly target neutrophilic inflammation because little is …

Adult patients with bronchiectasis: a first look at the US bronchiectasis research registry

TR Aksamit, AE O'Donnell, A Barker, KN Olivier… - Chest, 2017 - Elsevier
Objectives We sought to describe the characteristics of adult patients with bronchiectasis
enrolled in the US Bronchiectasis Research Registry (BRR). Methods The BRR is a …

Etiology of non–cystic fibrosis bronchiectasis in adults and its correlation to disease severity

S Lonni, JD Chalmers, PC Goeminne… - Annals of the …, 2015 - atsjournals.org
Rationale: Testing for underlying etiology is a key part of bronchiectasis management, but it
is unclear whether the same extent of testing is required across the spectrum of disease …

Geographic variation in the aetiology, epidemiology and microbiology of bronchiectasis

R Chandrasekaran, M Mac Aogáin, JD Chalmers… - BMC pulmonary …, 2018 - Springer
Bronchiectasis is a disease associated with chronic progressive and irreversible dilatation of
the bronchi and is characterised by chronic infection and associated inflammation. The …

The overlap between bronchiectasis and chronic airway diseases: state of the art and future directions

E Polverino, K Dimakou, J Hurst… - European …, 2018 - Eur Respiratory Soc
Bronchiectasis is a clinical and radiological diagnosis associated with cough, sputum
production and recurrent respiratory infections. The clinical presentation inevitably overlaps …