Inflammation and autophagy are cellular defense mechanisms. When these processes are
deregulated (deficient or overactivated) they produce pathologic effects, such as oxidative …

The identification of small subpopulations of cancer stem cells (CSCs) from blood
mononuclear cells in human acute myeloid leukemia (AML) in 1997 was a landmark …

Abstract miRNA (miR) 34a has been shown to modulate critical gene transcripts involved in
tumorigenesis, but its role in tumor-mediated immunosuppression is largely unknown. PD …

The purpose of this paper was to identify and summarize current evidence describing
periodontal complications associated with obesity. Electronic searches supplemented with …

Toll‐like receptors (TLRs), a critical family of pattern recognition receptors (PRRs), are
responsible for the innate immune responses via signalling pathways to provide effective …

Background Current evidence indicates that extracellular vesicles (EVs) participate in
intercellular signaling, and in the regulation and amplification of neuroinflammation. We …

The COVID-19 pandemic has emerged as a public health crisis and has placed a significant
burden on healthcare systems. Patients with underlying metabolic dysfunction, such as type …

The field of immunometabolism investigates and describes the effects of metabolic rewiring
in immune cells throughout activation and the fates of these cells. Recently, it has been …

The Kelch-like ECH-associated protein 1/nuclear factor erythroid-derived 2-like 2
(KEAP1/NRF2) pathway is well recognized as a key regulator of redox homeostasis …

Abstract MicroRNAs (miRNAs) are 20–22-nucleotide small endogenous non-coding RNAs
which regulate gene expression at post-transcriptional level. In the last two decades …