The discovery of kisspeptin as a critical central regulatory factor of GnRH release has given
people a novel understanding of the neuroendocrine regulation in human reproduction …

Reproduction involves a wide range of biological processes, including organ formation and
development, neuroendocrine regulation, hormone production, and meiosis and mitosis …

Increasing evidence accumulated during the past two decades has demonstrated that the
then-novel kisspeptin, which was discovered in 2001, the known neuropeptides neurokinin …

Gonadotropin hormone-releasing hormone (GnRH) is the key regulator of the reproductive
axis. Its pulsatile secretion determines the pattern of secretion of the gonadotropins follicle …

Kisspeptin (KP) and neurokinin B (NKB) are neuropeptides that govern the reproductive
endocrine axis through regulating hypothalamic gonadotropin-releasing hormone (GnRH) …

Polycystic ovary syndrome is a prevalent endocrinopathy involving androgen excess, and
anovulatory infertility. The disorder is also associated with many comorbidities such as …

Reproductive conditions secondary to disorders of the hypothalamic–pituitary–gonadal
(HPG) axis are common and are associated with important health implications and …

In late 2003, a major breakthrough in our understanding of the mechanisms that govern
reproduction occurred with the identification of the reproductive roles of kisspeptins …

Background Kisspeptin is the leading upstream regulator of pulsatile and surge
Gonadotrophin-Releasing Hormone secretion (GnRH) in the hypothalamus, which acts as …

Introduction Functional hypothalamic amenorrhoea (FHA) is a common form of secondary
amenorrhoea without an identifiable structural cause. Suppression of gonadotrophin …