Point-of-Care prostate specific antigen testing: examining translational progress toward clinical implementation

S Garg, A Sachdeva, M Peeters, J McClements - ACS sensors, 2023 - ACS Publications
Prostate cancer (PCa) is the second most common male cancer and is attributable to over
375,000 deaths annually. Prostate specific antigen (PSA) is a key biomarker for PCa and …

Merging microfluidics with luminescence immunoassays for urgent point-of-care diagnostics of COVID-19

H Yuan, P Chen, C Wan, Y Li, BF Liu - TrAC Trends in Analytical Chemistry, 2022 - Elsevier
Abstract The Coronavirus disease 2019 (COVID-19) outbreak has urged the establishment
of a global-wide rapid diagnostic system. Current widely-used tests for COVID-19 include …

Cobalt metal-organic framework modified carbon cloth/paper hybrid electrochemical button-sensor for nonenzymatic glucose diagnostics

X Wei, J Guo, H Lian, X Sun, B Liu - Sensors and Actuators B: Chemical, 2021 - Elsevier
In the growing pandemic, family healthcare is widely concerned with the increase of medical
self-diagnosis away from the hospital. A cobalt metal-organic framework modified carbon …

[HTML][HTML] Portable smartphone quantitation of prostate specific antigen (PSA) in a fluoropolymer microfluidic device

AI Barbosa, P Gehlot, K Sidapra, AD Edwards… - Biosensors and …, 2015 - Elsevier
We present a new, power-free and flexible detection system named MCFphone for portable
colorimetric and fluorescence quantitative sandwich immunoassay detection of prostate …

Self-contained microfluidic systems: a review

M Boyd-Moss, S Baratchi, M Di Venere… - Lab on a Chip, 2016 - pubs.rsc.org
Microfluidic systems enable rapid diagnosis, screening and monitoring of diseases and
health conditions using small amounts of biological samples and reagents. Despite these …

Microfluidic blood plasma separation for medical diagnostics: is it worth it?

WS Mielczarek, EA Obaje, TT Bachmann… - Lab on a Chip, 2016 - pubs.rsc.org
Circulating biomarkers are on the verge of becoming powerful diagnostic tools for various
human diseases. However, the complex sample composition makes it difficult to detect …

A critical insight into the development pipeline of microfluidic immunoassay devices for the sensitive quantitation of protein biomarkers at the point of care

AI Barbosa, NM Reis - Analyst, 2017 - pubs.rsc.org
The latest clinical procedures for the timely and cost-effective diagnosis of chronic and acute
clinical conditions, such as cardiovascular diseases, cancer, chronic respiratory diseases …

Capillary-driven flow microfluidics combined with smartphone detection: an emerging tool for point-of-care diagnostics

S Hassan, A Tariq, Z Noreen, A Donia, SZJ Zaidi… - Diagnostics, 2020 - mdpi.com
Point-of-care (POC) or near-patient testing allows clinicians to accurately achieve real-time
diagnostic results performed at or near to the patient site. The outlook of POC devices is to …

Immunoassay for detection of infliximab in whole blood using a fiber-optic surface plasmon resonance biosensor

J Lu, D Spasic, F Delport, T Van Stappen… - Analytical …, 2017 - ACS Publications
Monitoring the concentration of a therapeutic drug antibody, infliximab (IFX), is
recommended for enhancing its efficacy in patients with inflammatory bowel disease (IBD) …

Gravity-driven microfluidic siphons: fluidic characterization and application to quantitative immunoassays

NM Reis, SH Needs, SM Jegouic, KK Gill… - ACS …, 2021 - ACS Publications
A range of biosensing techniques including immunoassays are routinely used for
quantitation of analytes in biological samples and available in a range of formats, from …