Therapeutic potential of boron-containing compounds
SJ Baker, CZ Ding, T Akama, YK Zhang… - Future medicinal …, 2009 - Taylor & Francis
Relative to carbon, hydrogen, nitrogen and oxygen, very little is currently known about boron
in therapeutics. In addition, there are very few boron-containing natural products identified to …
in therapeutics. In addition, there are very few boron-containing natural products identified to …
Boron Neutron Capture Therapy (BNCT) for Cutaneous Malignant Melanoma Using 10Bp-Boronophenylalanine (BPA) with Special Reference to the Radiobiological …
H Fukuda - Cells, 2021 - mdpi.com
BNCT is a radiotherapeutic method for cancer treatment that uses tumor-targeting 10B-
compounds. BNCT for cutaneous melanoma using BPA, a phenylalanine derivative, was …
compounds. BNCT for cutaneous melanoma using BPA, a phenylalanine derivative, was …
Acute and subchronic toxicity analysis of surface modified paclitaxel attached hydroxyapatite and titanium dioxide nanoparticles
GD Venkatasubbu, S Ramasamy… - International journal …, 2015 - Taylor & Francis
Nanoparticles are widely used for targeted drug delivery applications. Surface modification
with appropriate polymer and ligands is carried out to target the drug to the affected area …
with appropriate polymer and ligands is carried out to target the drug to the affected area …
Susceptibility to hydrolysis of phenylboronic pinacol esters at physiological pH
Boronic acids and their esters are highly considered compounds for the design of new drugs
and drug delivery devices, particularly as boron-carriers suitable for neutron capture …
and drug delivery devices, particularly as boron-carriers suitable for neutron capture …
Boron nanoparticles in chemotherapy and radiotherapy: the synthesis, state-of-the-art, and prospects
SA Uspenskii, PA Khaptakhanova - Russian Chemical Bulletin, 2022 - Springer
Boron neutron capture therapy (BNCT) is a radiotherapy method for cancer treatment based
on the nuclear reaction of the stable 10B isotope with epithermal neutrons that produces …
on the nuclear reaction of the stable 10B isotope with epithermal neutrons that produces …
Selective thermal neutron capture therapy of cancer cells using their specific metabolic activities—melanoma as prototype
Y Mishima - Cancer neutron capture therapy, 1996 - Springer
It was around 1972 when it occurred to me that the accentuated melanogenesis occurring
parallel and specific to the transformation of pigment cells to malignant melanoma could be …
parallel and specific to the transformation of pigment cells to malignant melanoma could be …
Drugs for BNCT: BSH and BPA
WAG Sauerwein, PM Bet, A Wittig - Neutron Capture Therapy: Principles …, 2012 - Springer
This chapter is based on a shortened version of the investigators brochures from the EORTC
clinical trials 11001 and 11011 concerning the boron compounds sodium borocaptate (BSH) …
clinical trials 11001 and 11011 concerning the boron compounds sodium borocaptate (BSH) …
4-Borono-2-[18F] fluoro-D, L-phenylalanine: a possible tracer for melanoma diagnosis with PET
K Ishiwata, T Ido, C Honda, M Kawamura… - International journal of …, 1992 - Elsevier
Abstract The potential of 4-borono-2-[18 F] fluoro-d, l-phenylalanine ([18 F] FBPA), a
fluorinated derivative of a target compound for boron neutron capture therapy, for melanoma …
fluorinated derivative of a target compound for boron neutron capture therapy, for melanoma …
Selective thermal neutron capture therapy and diagnosis of malignant melanoma: from basic studies to first clinical treatment
Y Mishima, M Ichihashi, S Hatta, C Honda… - Clinical Aspects of …, 1989 - Springer
As melanoma genesis occurs in pigment cells, accentuated melanogenesis concurrently
occurs in principlel. Thus, harnessing this accentuation of melanogenesis, we developed a …
occurs in principlel. Thus, harnessing this accentuation of melanogenesis, we developed a …
Boron neutron capture therapy of intracerebral melanoma using boronophenylalanine as a capture agent
KZ Matalka, MQ Bailey, RF Barth, AE Staubus… - Cancer research, 1993 - AACR
A rat brain tumor model has been developed utilizing nude rats and the human melanoma
cell line MRA 27. For pharmacokinetic and tissue distribution studies, 2 105 MRA 27 cells …
cell line MRA 27. For pharmacokinetic and tissue distribution studies, 2 105 MRA 27 cells …