Chemical diversity and bioactivities of monoterpene indole alkaloids (MIAs) from six Apocynaceae genera

AE Mohammed, ZH Abdul-Hameed, MO Alotaibi… - Molecules, 2021 - mdpi.com
By the end of the twentieth century, the interest in natural compounds as probable sources of
drugs has declined and was replaced by other strategies such as molecular target-based …

New glycocerebrosides from the trunk of Tabernaemontana contorta Stapf.(Apocynaceae) and their antibacterial activity

GR Ebede, JN Mbing, AB Nama, N Shehla… - Biochemical Systematics …, 2022 - Elsevier
Phytochemical investigation of the trunk of Tabernaemontana contorta Stapf. led to the
isolation and identification of two new glycocerebrosides, tabernamides A (1) and B (2) …

Antimicrobial and cytotoxic activities of indole alkaloids and other constituents from the stem barks of Rauvolfia caffra Sond (Apocynaceae)

AN Bitombo, AAA Zintchem, AT Atchade… - Natural Product …, 2022 - Taylor & Francis
Twenty indole alkaloids, among which two undescribed ones named rauvolfianoids A (1)
and B (2), were isolated from the stem barks of Rauvolfia caffra Sond along with eight other …

Fourteen undescribed steroidal saponins from Solanum capsicoides leaves and their neuroprotective effects

Y Liu, XY Li, J Wu, H Wang, X Meng, HD Zou, J Pan… - Phytochemistry, 2024 - Elsevier
A total of 14 previously undescribed steroidal saponins named capsicsaponins A–N were
isolated from the leaves of Solanum capsicoides, encompassing various types, including …

Contortamide, a new anti-colon cancer cerebroside and other constituents from Tabernaemontana contorta Stapf (Apocynaceae)

GR Ebede, JT Ndongo, JN Mbing… - Natural product …, 2021 - Taylor & Francis
Abstract A new cerebroside, Contortamide (1) together with nine known compounds
spegatrine (2), affinisine (3), Nb-methylaffinisine (4), ursolic acid (5), α-amyrin (6), bauerenol …

A new cytotoxic indole alkaloid from Tabernaemontana inconspicua stapf

G Foudjo Melacheu Laura, E Mfotie Njoya… - Natural Product …, 2021 - Taylor & Francis
One new indole alkaloid derivative, 5, 6-dioxo-11-hydroxy voacangine (1) together with four
known compounds (2-5), were isolated from the fruits of Tabernaemontana inconspicua …

Biological activity and 13C NMR spectral data of iboga-type skeleton alkaloids

FD de Lourdes, MS Passos, R Braz-Filho… - Studies in Natural …, 2022 - Elsevier
Among the numerous substances discovered by the Chemistry of Natural Products, the
monoterpenicindolic alkaloids are the main constituents of the Tabernaemontana genus of …

Structural activity analysis, spectroscopic investigation, biological and chemical properties interpretation on Beta Carboline using quantum computational methods

K Hemachandran, P Anbusrinivasan, S Ramalingam… - Heliyon, 2019 - cell.com
In this methodological work, the structural activity analysis have been carried out on β-
Carboline to study the anti cancer activity and the way of improving the biological activity …

A New Antimicrobial Phenylpropanol from the Leaves of Tabernaemontana inconspicua Stapf. (Apocynaceae) Inhibits Pathogenic Gram-Negative Bacteria

L Ngah, WDT Tsopgni, JCN Nyobe, AT Tcho… - Antibiotics, 2022 - mdpi.com
A chemical investigation of the leaves of Tabernaemontana inconspicua Stapf. led to the
isolation of a new phenylpropanol derivative, namely irisdichototin G (1), together with nine …

[PDF][PDF] Indole Alkaloids and Antimalarial Activity in the Tabernaemontana Species

AT Hutami, M Rudyanto… - Jurnal Farmasi dan Ilmu …, 2024 - e-journal.unair.ac.id
Abstract Background: Malaria, caused by Plasmodium parasites, is a highly prevalent and
lethal illness that shows persistent ability to develop resistance. Antiplasmodial compounds …