Fibrinogen is the substrate of plasma coagulation. It plays an important role in the formation
of reticular network, which is crucial to the strength and stability of blood clots. In addition to …

Traumatic brain injury (TBI) and severe blood loss (SBL) frequently co-occur in human
trauma, resulting in high levels of mortality and morbidity. Importantly, each of the individual …

Objectives: Explain the definition of shock. Summarize the evaluation of hemorrhagic shock.
Outline management options available for the treatment of hemorrhagic shock. Identify some …

Introduction: The optimal management strategies for patients with polytraumatic injuries that
include traumatic brain injury (TBI) are not well defined. Specific interventions including …

Frontiers | Traumatic Brain Injury—A Review of Intravenous Fluid Therapy Skip to main
content Download Article Download Article Download PDF ReadCube EPUB XML (NLM) …

Objectives Trauma-induced hemorrhagic shock is characterized by increased endothelial
permeability and coagulopathy. Vasopressin analog ddAVP (desmopressin) acts by …

Background: The clinical impact of vasopressin in hemorrhagic shock remains largely
unknown. Objective: This systematic review and meta-analysis was designed to investigate …

Thoracoabdominal and transmediastinal injuries represent some of the most challenging
injuries facing trauma surgeons. The diagnostic challenge of multiple body cavity injuries …

Background The benefits of vasopressor (VP) use to improve clinical outcomes in traumatic
brain injury (TBI) is unknown. We sought to characterize the use of VP in TBI patients and …

The resuscitation of polytrauma with hemorrhagic shock and traumatic brain injury (TBI) is a
balance between permissive hypotension and maintaining vital organ perfusion. There is no …