[HTML][HTML] Autophagy in Alzheimer's disease pathogenesis: Therapeutic potential and future perspectives

Z Zhang, X Yang, YQ Song, J Tu - Ageing research reviews, 2021 - Elsevier
Alzheimer's disease (AD) is a complex neurodegenerative disease in the elderly and the
most common cause of human dementia. AD is characterized by accumulation of abnormal …

Nutraceutical approach to chronic osteoarthritis: from molecular research to clinical evidence

A Colletti, AFG Cicero - International journal of molecular sciences, 2021 - mdpi.com
Osteoarthritis (OA) is a degenerative inflammatory condition of the joint cartilage that
currently affects approximately 58 million adults in the world. It is characterized by pain …

Relative efficacy and safety of topical non-steroidal anti-inflammatory drugs for osteoarthritis: a systematic review and network meta-analysis of randomised controlled …

C Zeng, J Wei, MSM Persson, A Sarmanova… - British journal of sports …, 2018 - bjsm.bmj.com
Objectives To compare the efficacy and safety of topical non-steroidal anti-inflammatory
drugs (NSAIDs), including salicylate, for the treatment of osteoarthritis (OA). Methods …

The efficacy and safety of disease-modifying osteoarthritis drugs for knee and hip osteoarthritis—a systematic review and network meta-analysis

W Yang, C Sun, SQ He, JY Chen, Y Wang… - Journal of General …, 2021 - Springer
Background Osteoarthritis (OA) is common and burdensome for patients and health care
systems. Our study purpose was to evaluate the long-term efficacy and safety of DMOADs in …

Safety of symptomatic slow-acting drugs for osteoarthritis: outcomes of a systematic review and meta-analysis

G Honvo, JY Reginster, V Rabenda, A Geerinck… - Drugs & aging, 2019 - Springer
Background Symptomatic slow-acting drugs for osteoarthritis (SYSADOAs) are an important
drug class in the treatment armamentarium for osteoarthritis (OA). Objective We aimed to re …

Non-steroidal anti-inflammatory drug (NSAID) therapy in patients with hypertension, cardiovascular, renal or gastrointestinal comorbidities: joint APAGE/APLAR …

CC Szeto, K Sugano, JG Wang, K Fujimoto, S Whittle… - Gut, 2020 - gut.bmj.com
Background Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most commonly
prescribed medications, but they are associated with a number of serious adverse effects …

[HTML][HTML] Towards natural mimetics of metformin and rapamycin

A Aliper, L Jellen, F Cortese, A Artemov… - Aging (albany …, 2017 - ncbi.nlm.nih.gov
Aging is now at the forefront of major challenges faced globally, creating an immediate need
for safe, widescale interventions to reduce the burden of chronic disease and extend human …

Nonoperative treatments for knee osteoarthritis: an evaluation of treatment characteristics and the intra-articular placebo effect: a systematic review

C Vannabouathong, M Bhandari, A Bedi, V Khanna… - JBJS …, 2018 - journals.lww.com
Background: Guidelines recommending various nonoperative treatments for patients with
knee osteoarthritis remain inconsistent. Much of this controversy relates to what constitutes a …

Influence of a low‐dose supplementation of curcumagalactomannoside complex (CurQfen) in knee osteoarthritis: A randomized, open‐labeled, active‐controlled …

JV Thomas, TP Smina, A Khanna… - Phytotherapy …, 2021 - Wiley Online Library
A 6‐week, randomized, open‐label, active‐controlled clinical trial was conducted to
evaluate the influence of a low‐dose curcumagalactomannosides (CGM)(400 mg once …

[HTML][HTML] Reunión multidisciplinaria de expertos para el diagnóstico y tratamiento de la osteoartritis. Actualización basada en evidencias

R Espinosa-Morales, J Alcántar-Ramírez… - Medicina interna de …, 2018 - scielo.org.mx
La osteoartritis es una enfermedad articular crónica degenerativa, es la afección articular
observada con más frecuencia en la población adulta y una de las principales causas de …