Neurobiology of glycine transporters: From molecules to behavior
BL Marques, OC Oliveira-Lima, GA Carvalho… - Neuroscience & …, 2020 - Elsevier
Abstract Glycine transporters (GlyTs) are Na+/Cl−-dependent neurotransmitter transporters,
responsible for l-glycine uptake into the central nervous system. GlyTs are members of the …
responsible for l-glycine uptake into the central nervous system. GlyTs are members of the …
Is there a glutathione centered redox dysregulation subtype of schizophrenia?
Schizophrenia continues to be an illness with poor outcome. Most mechanistic changes
occur many years before the first episode of schizophrenia; these are not reversible after the …
occur many years before the first episode of schizophrenia; these are not reversible after the …
In Vitro and In Vivo Neuroprotective Effects of Sarcosine
A Tanas, ÖÖ Tozlu, T Gezmiş… - BioMed research …, 2022 - Wiley Online Library
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by behavioral and
psychological symptoms in addition to cognitive impairment and loss of memory. The exact …
psychological symptoms in addition to cognitive impairment and loss of memory. The exact …
Sarcosine (glycine transporter inhibitor) attenuates behavioural and biochemical changes induced by ketamine, in the rat model of schizophrenia
Schizophrenia is a neurological disorder that alters the behavior and affects the quality of life
of a patient. It is characterized by hallucinations, disorganized behavior, cognitive …
of a patient. It is characterized by hallucinations, disorganized behavior, cognitive …
NMR-based metabonomics and correlation analysis reveal potential biomarkers associated with chronic atrophic gastritis
J Cui, Y Liu, Y Hu, J Tong, A Li, T Qu, X Qin… - Journal of Pharmaceutical …, 2017 - Elsevier
Chronic atrophic gastritis (CAG) is one of the most important pre-cancerous states with a
high prevalence. Exploring of the underlying mechanism and potential biomarkers is of …
high prevalence. Exploring of the underlying mechanism and potential biomarkers is of …
Design, synthesis and biological evaluation of diosgenin-amino acid derivatives with dual functions of neuroprotection and angiogenesis
D Cai, J Qi, Y Yang, W Zhang, F Zhou, X Jia, W Guo… - Molecules, 2019 - mdpi.com
Diosgenin, a natural product with steroidal structure, has a wide range of clinical
applications in China. It also shows great potential in the treatment of blood clots and nerve …
applications in China. It also shows great potential in the treatment of blood clots and nerve …
Effects of blast overpressure on neurons and glial cells in rat organotypic hippocampal slice cultures
Due to recent involvement in military conflicts, and an increase in the use of explosives,
there has been an escalation in the incidence of blast-induced traumatic brain injury (bTBI) …
there has been an escalation in the incidence of blast-induced traumatic brain injury (bTBI) …
GlyT1 Inhibition by NFPS Promotes Neuroprotection in Amyloid-β-Induced Alzheimer's Disease Animal Model
OC Oliveira-Lima, GA de Carvalho… - Neurochemical …, 2024 - Springer
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the
accumulation of amyloid-β, leading to N-methyl-D-aspartate (NMDA) receptor-dependent …
accumulation of amyloid-β, leading to N-methyl-D-aspartate (NMDA) receptor-dependent …
Glycine transporters type 1 inhibitor promotes brain preconditioning against NMDA-induced excitotoxicity
MCX Pinto, IV de Assis Lima, FLP da Costa, DV Rosa… - …, 2015 - Elsevier
Brain preconditioning is a protective mechanism, which can be activated by sub-lethal
stimulation of the NMDA receptors (NMDAR) and be used to achieve neuroprotection …
stimulation of the NMDA receptors (NMDAR) and be used to achieve neuroprotection …
Neuroprotection mediated by remote preconditioning is associated with a decrease in systemic oxidative stress and changes in brain and blood glutamate …
J Jachova, M Gottlieb, M Nemethova… - Neurochemistry …, 2019 - Elsevier
It has been shown that ischemia of remote organs can generate resistance to ischemic
conditions within sensitive brain tissues. However, only limited information about its …
conditions within sensitive brain tissues. However, only limited information about its …