The nuclear factor-kappaB (NF-κB) signaling pathway is considered as a potential
therapeutic target in cancer therapy. It has been well established that transcription factor NF …

Rapid advancements in materials science and nanotechnology, intertwined with oncology,
have positioned photothermal therapy (PTT) as a promising noninvasive treatment strategy …

Although programmed death-ligand 1 (PD-L1) inhibitors have achieved some therapeutic
success in breast cancer, their efficacy is limited by low therapeutic response rates, which is …

Cancer is the second leading cause of death worldwide. Majority of recent research efforts in
the field aim to address why cancer resistance to therapy develops and how to overcome or …

The combination of an immuno-metabolic adjuvant and immune checkpoint inhibitors holds
great promise for effective suppression of tumor growth and invasion. In this study, a pH …

Advances in computational algorithms and tools have made the prediction of cancer patient
outcomes using computational pathology feasible. However, predicting clinical outcomes …

Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer.
Altered epigenetics regulation including DNA hypermethylation by DNA methyltransferase 1 …

Abstract Programmed death-1 (PD-1) and its ligand programmed death-ligand 1 (PD-L1)
help tumor cells evade immune surveillance, and are regarded as important targets of anti …

Simple Summary Despite the increased use of neoadjuvant chemotherapy in the early
setting of breast cancer, there is a clinical need for predictive markers of response in daily …

Diacylglycerol (DAG) is a lipid second messenger that is generated in response to
extracellular stimuli and channels intracellular signals that affect mammalian cell …