Fibrin polymer on the surface of biomaterial implants drives the foreign body reaction
Implantation of biomaterials and medical devices in the body triggers the foreign body
reaction (FBR) which is characterized by macrophage fusion at the implant surface leading …
reaction (FBR) which is characterized by macrophage fusion at the implant surface leading …
An actin-based protrusion originating from a podosome-enriched region initiates macrophage fusion
JJ Faust, A Balabiyev, JM Heddleston… - Molecular biology of …, 2019 - Am Soc Cell Biol
Macrophage fusion resulting in the formation of multinucleated giant cells occurs in a variety
of chronic inflammatory diseases, yet the mechanism responsible for initiating this process is …
of chronic inflammatory diseases, yet the mechanism responsible for initiating this process is …
Transition of podosomes into zipper-like structures in macrophage-derived multinucleated giant cells
A Balabiyev, NP Podolnikova… - Molecular biology of …, 2020 - Am Soc Cell Biol
Macrophage fusion resulting in the formation of multinucleated giant cells (MGCs) is a
multistage process that requires many adhesion-dependent steps and involves the …
multistage process that requires many adhesion-dependent steps and involves the …
The CIS association of CD47 with integrin Mac-1 regulates macrophage responses by stabilizing the extended integrin conformation
NP Podolnikova, S Key, X Wang, TP Ugarova - Journal of Biological …, 2023 - ASBMB
CD47 is a ubiquitously expressed cell surface integrin-associated protein. Recently, we
have demonstrated that integrin Mac-1 (α M β 2, CD11b/CD18, CR3), the major adhesion …
have demonstrated that integrin Mac-1 (α M β 2, CD11b/CD18, CR3), the major adhesion …