Women are at twice the risk for anxiety and depression disorders as men are, although the
underlying biological factors and mechanisms are largely unknown. In this review, we …

Sex differences are found across brain regions, behaviors, and brain diseases. Sexual
differentiation of the brain is initiated prenatally but it continues throughout life, as a result of …

The activity of neurons in the rodent hippocampus contributes to diverse behaviors, with the
activity of ventral hippocampal neurons affecting behaviors related to anxiety and emotion …

Depression is a serious neuropsychiatric disease affecting an increasing number of people
worldwide. Cognitive deficits (including inattention, poor memory, and decision-making …

Klotho (KL) is a glycosyl hydrolase and aging-suppressor gene. Stress is a risk factor for
depression and anxiety, which are highly comorbid with each other. The aim of this study is …

Soil carbon supplementation is known to stimulate plant growth by improving soil fertility and
plant nutrient uptake. However, the underlying process and chemical mechanism that could …

Extracellular vesicles (EVs) are produced by all cells in the body. These biological
nanoparticles facilitate cellular communication through the transport of diverse cargoes …

G protein-coupled estrogen receptor (GPER) in the amygdala and the dorsal hippocampus
mediates actions of estradiol on anxiety, social recognition and spatial memory. In addition …

Exercise facilitates hippocampal neurogenesis and neuroplasticity that in turn, promotes
cognitive function. Our previous studies have demonstrated that in male mice, voluntary …

Sex differences have complicated our understanding of the neurobiological basis of many
behaviors that are key for survival. As such, continued elucidation of the similarities and …