Fascin actin-bundling protein 1 (FSCN1) is a highly conserved actin-bundling protein that
cross links F-actin microfilaments into tight, parallel bundles. Elevated FSCN1 levels have …

Simple Summary Cell migration is an essential biological process that regulates both
development and diseases, such as cancer metastasis. Therefore, understanding the factors …

Background Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast
cancer with poor prognosis, and its treatment remains a challenge due to few targeted …

Fascin actin-bundling protein 1 (FSCN1) is an actin-bundling protein that is capable of
inducing membrane protrusions and plays critical roles in cell migration, motility, adhesion …

Serrated adenocarcinoma (SAC) is more invasive, has worse outcomes than conventional
colorectal carcinoma (CRC), and is characterized by frequent resistance to anti-epidermal …

Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype. To
identify TNBC therapeutic targets, we performed integrative bioinformatics analysis of …

In some cases of breast cancer, diagnosis of triple‐negative breast cancer (TNBC) requires
further fluorescence in situ hybridization (FISH) for determining human epidermal growth …

Emerging evidence indicates that Fascin-1 (FSCN1) may possess a causal role in the
development of several types of cancers and serves as a novel biomarker of aggressiveness …

Breast cancer is a major cause of cancer mortality worldwide. Fascin-1 (FSCN1) is an actin-
binding protein found in mammalian cells, including endothelial, neuronal and …

Simple Summary Tricyclic antidepressants (TCAs) are old and known therapeutic agents
whose good safety profile makes them good candidates for drug repurposing. As the …