Systemic impact of heavy metals and their role in cancer development: a review

L Parida, TN Patel - Environmental Monitoring and Assessment, 2023 - Springer
Heavy metals are well-recognised as environmental hazards due to their toxicity,
environmental persistence, and bioaccumulation in living organisms. Human health is a …

[HTML][HTML] Epigenetics across the human lifespan

RR Kanherkar, N Bhatia-Dey, AB Csoka - Frontiers in cell and …, 2014 - frontiersin.org
Epigenetics has the potential to explain various biological phenomena that have heretofore
defied complete explication. This review describes the various types of endogenous human …

Metals and molecular carcinogenesis

Y Zhu, M Costa - Carcinogenesis, 2020 - academic.oup.com
Many metals are essential for living organisms, but at higher doses they may be toxic and
carcinogenic. Metal exposure occurs mainly in occupational settings and environmental …

Arsenic and human health: genotoxicity, epigenomic effects, and cancer signaling

M Ozturk, M Metin, V Altay, RA Bhat, M Ejaz… - … Trace Element Research, 2022 - Springer
Arsenic is a well-known element because of its toxicity. Humans as well as plants and
animals are negatively affected by its exposure. Some countries suffer from high levels of …

A review on arsenic carcinogenesis: epidemiology, metabolism, genotoxicity and epigenetic changes

Q Zhou, S Xi - Regulatory Toxicology and Pharmacology, 2018 - Elsevier
Long-term exposure to arsenic (inorganic arsenic) is a world-wide environmental health
concern. Arsenic is classified as the Group 1 human carcinogen by the International Agency …

Arsenic exposure and the induction of human cancers

VD Martinez, EA Vucic, DD Becker-Santos… - Journal of …, 2011 - Wiley Online Library
Arsenic is a metalloid, that is, considered to be a human carcinogen. Millions of individuals
worldwide are chronically exposed through drinking water, with consequences ranging from …

Environmental chemical exposures and human epigenetics

L Hou, X Zhang, D Wang… - International journal of …, 2012 - academic.oup.com
Every year more than 13 million deaths worldwide are due to environmental pollutants, and
approximately 24% of diseases are caused by environmental exposures that might be …

[HTML][HTML] Arsenic causing gallbladder cancer disease in Bihar

A Kumar, M Ali, V Raj, A Kumari, M Rachamalla… - Scientific reports, 2023 - nature.com
In recent times Gallbladder cancer (GBC) incidences increased many folds in India and are
being reported from arsenic hotspots identified in Bihar. The study aims to establish …

Genome-scale analysis of DNA methylation in lung adenocarcinoma and integration with mRNA expression

SA Selamat, BS Chung, L Girard, W Zhang… - Genome …, 2012 - genome.cshlp.org
Lung cancer is the leading cause of cancer death worldwide, and adenocarcinoma is its
most common histological subtype. Clinical and molecular evidence indicates that lung …

Effects of arsenic exposure on DNA methylation and epigenetic gene regulation

JF Reichard, A Puga - Epigenomics, 2010 - Taylor & Francis
Arsenic is a nonmutagenic human carcinogen that induces tumors through unknown
mechanisms. A growing body of evidence suggests that its carcinogenicity results from …