An ecologist's guide for studying DNA methylation variation in wild vertebrates

VN Laine, B Sepers, M Lindner… - Molecular Ecology …, 2023 - Wiley Online Library
The field of molecular biology is advancing fast with new powerful technologies, sequencing
methods and analysis software being developed constantly. Commonly used tools originally …

[HTML][HTML] The epigenetics of animal personality

K van Oers, K van den Heuvel, B Sepers - Neuroscience & Biobehavioral …, 2023 - Elsevier
Animal personality, consistent individual differences in behaviour, is an important concept
for understanding how individuals vary in how they cope with environmental challenges. In …

Variation in DNA methylation in avian nestlings is largely determined by genetic effects

B Sepers, RS Chen, M Memelink… - Molecular Biology …, 2023 - academic.oup.com
As environmental fluctuations are becoming more common, organisms need to rapidly adapt
to anthropogenic, climatic, and ecological changes. Epigenetic modifications and DNA …

Rapid changes in DNA methylation associated with the initiation of reproduction in a small songbird

M Lindner, VN Laine, I Verhagen… - Molecular …, 2021 - Wiley Online Library
Species with a circannual life cycle need to match the timing of their life history events to the
environment to maximize fitness. However, our understanding of how circannual traits such …

Developmental stress does not induce genome‐wide DNA methylation changes in wild great tit (Parus major) nestlings

B Sepers, AC Mateman, F Gawehns… - Molecular …, 2023 - Wiley Online Library
The environment experienced during early life is a crucial factor in the life of many
organisms. This early life environment has been shown to have profound effects on …

Epigenetics and Early Life Stress: Experimental Brood Size Affects DNA Methylation in Great Tits (Parus major)

B Sepers, JAM Erven, F Gawehns, VN Laine… - Frontiers in Ecology …, 2021 - frontiersin.org
Early developmental conditions are known to have life-long effects on an individual's
behavior, physiology and fitness. In altricial birds, a majority of these conditions, such as the …

Genetic and epigenetic differentiation in response to genomic selection for avian lay date

M Lindner, I Verhagen, AC Mateman… - Evolutionary …, 2024 - Wiley Online Library
Anthropogenic climate change has led to globally increasing temperatures at an
unprecedented pace and, to persist, wild species have to adapt to their changing world. We …

Multi-adaptive Neural Modelling of the Interplay of Changing Organisational Contexts, Epigenetics, and Personality Traits in the Development of Burnout

D Bouma, J Treur - IFIP International Conference on Artificial Intelligence …, 2024 - Springer
This research addresses the influence of a changing organisational context and the big five
personality traits on the three main characterising elements of a burnout. A computational …

Performance of methods to detect genetic variants from bisulphite sequencing data in a non‐model species

M Lindner, F Gawehns, S Te Molder… - Molecular Ecology …, 2022 - Wiley Online Library
The profiling of epigenetic marks like DNA methylation has become a central aspect of
studies in evolution and ecology. Bisulphite sequencing is commonly used for assessing …

Epigenomics as a paradigm to understand the nuances of phenotypes

C Fanter, C Madelaire, DP Genereux… - Journal of …, 2022 - journals.biologists.com
Quantifying the relative importance of genomic and epigenomic modulators of phenotype is
a focal challenge in comparative physiology, but progress is constrained by availability of …