Retinoblastoma

H Dimaras, TW Corson, D Cobrinik, A White… - Nature reviews Disease …, 2015 - nature.com
Retinoblastoma is a rare cancer of the infant retina that is diagnosed in approximately 8,000
children each year worldwide. It forms when both retinoblastoma gene (RB1) alleles are …

Conservative management of retinoblastoma: Challenging orthodoxy without compromising the state of metastatic grace.“Alive, with good vision and no comorbidity”

FL Munier, M Beck-Popovic, GL Chantada… - Progress in retinal and …, 2019 - Elsevier
Retinoblastoma is lethal by metastasis if left untreated, so the primary goal of therapy is to
preserve life, with ocular survival, visual preservation and quality of life as secondary aims …

Treatment of retinoblastoma in 2015: agreement and disagreement

DH Abramson, CL Shields, FL Munier… - JAMA …, 2015 - jamanetwork.com
The management of intraocular retinoblastoma is rapidly changing, and even recent reviews
on the subject are behind existing practices. The 4 authors of this report collectively …

Intra-arterial chemotherapy for the management of retinoblastoma: four-year experience

YP Gobin, IJ Dunkel, BP Marr, SE Brodie… - Archives of …, 2011 - jamanetwork.com
Objective: To determine whether intra-arterial chemotherapy is safe and effective in
advanced intraocular retinoblastoma. Retinoblastoma often presents with advanced …

A phase I/II study of direct intraarterial (ophthalmic artery) chemotherapy with melphalan for intraocular retinoblastoma: initial results

DH Abramson, IJ Dunkel, SE Brodie, JW Kim, YP Gobin - Ophthalmology, 2008 - Elsevier
OBJECTIVE: To develop a technique that would allow us to cannulate repeatedly the
ophthalmic artery of young children with advanced retinoblastoma, to find a dose of …

Retinoblastoma

I Aerts, L Lumbroso-Le Rouic… - Orphanet journal of rare …, 2006 - Springer
Retinoblastoma is a rare eye tumor of childhood that arises in the retina. It is the most
common intraocular malignancy of infancy and childhood; with an incidence of 1/15,000 …

Superselective ophthalmic artery chemotherapy as primary treatment for retinoblastoma (chemosurgery)

DH Abramson, IJ Dunkel, SE Brodie, B Marr, YP Gobin - Ophthalmology, 2010 - Elsevier
PURPOSE: To report on our 3-year experience with the use of superselective ophthalmic
artery infusion of chemotherapy as initial, primary treatment for intraocular retinoblastoma …

Retinoblastoma in the 20th century: past success and future challenges the Weisenfeld lecture

DH Abramson - Investigative ophthalmology & visual science, 2005 - iovs.arvojournals.org
Retinoblastoma is the most common primary cancer of the eye in children. 1 Although it
represents only approximately 4% of childhood cancer and less than 1% of all human …

Proceedings of the consensus meetings from the International Retinoblastoma Staging Working Group on the pathology guidelines for the examination of enucleated …

X Sastre, GL Chantada, F Doz… - … of pathology & …, 2009 - meridian.allenpress.com
Retinoblastoma is the most common intraocular malignant childhood tumor in need of
prospective clinical trials to address important unanswered questions about biology …

Retinoblastoma: saving life with vision

DH Abramson - Annual review of medicine, 2014 - annualreviews.org
Retinoblastoma has gone from> 95% mortality to> 95% survival in the past 100 years. Once
enucleation techniques were perfected, the majority of children survived, but without the eye …